Cardiology Studies

Anti-ischemic Effect of Monoterpene Citronellol on Experimental Stroke Models Mediated by Pro-inflammatory Cytokines.

Researchers studied the effectiveness of citronellol, a compound found in certain plants, in treating cerebral ischemia (a type of stroke). They found that citronellol has potential as an alternative therapy due to its low cost and minimal side effects. Citronellol also has various pharmacological properties that may aid in stroke treatment.

Liu X, Zhu C and Yin Y (2023).
Comb Chem High Throughput Screen.
PubMed:
36372917

Leonurine attenuates angiotensin II-induced cardiac injury and dysfunction via inhibiting MAPK and NF-κB pathway.

Researchers investigated the effects of leonurine on hypertensive cardiac injury caused by angiotensin II (Ang II). Leonurine, an active compound found in the traditional Chinese herb Leonurus japonicus Houtt, has potential in treating hypertensive cardiac alterations such as hypertrophy, fibrosis, and dysfunction. Results suggest that leonurine significantly attenuated Ang II-induced cardiac injury, reducing fibrosis and inflammation. These findings indicate that leonurine may have cardioprotective effects and potential as a therapeutic agent for hypertensive heart disease.

Shen S et al (2023).
Phytomedicine.
PubMed:
36332391

Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.

Ahmad H et al (2022).
J Food Biochem.
PubMed:
36314446