Sappanone A: A natural PDE4 inhibitor with dual anti-inflammatory and antioxidant activities from the heartwood of Caesalpinia sappan L.
- Wang YZ et al (2023).
- J Ethnopharmacol.
- PubMed:
- 36529254
Kaixin San (KXS) is a traditional Chinese medicine used for emotion-thought diseases. Researchers investigated whether it benefits hippocampal neurons and myocardial cells of mice with paradoxical sleep deprivation (PSD) and its mechanism. KXS was found to effectively improve PSD-induced damage to the hippocampus and myocardium, likely due to its anti-inflammatory and antioxidant properties. These findings suggest KXS may be a potential treatment for sleep deprivation-related diseases.