A Novel Extract From Ginkgo biloba Inhibits Neuroinflammation and Maintains White Matter Integrity in Experimental Stroke.

Pinitol added to GBE reduces brain damage, improves function, promotes white matter repair, and inhibits inflammation in stroke mice, suggesting potential as a treatment for stroke patients.

Dong W et al (2023).

Neuroscience.

DOI:

10.1016/j.neuroscience.2023.05.015

PubMed:

37225050

Acmella oleracea induced nanostructured Ca(2)Fe(2)O(5) for evaluation of photo catalytic degradation of cardiovascular drugs and bio toxicity.

Scientists used a plant extract to create nanocrystalline CaFeO, which showed high photocatalytic and antibacterial activity, as well as low cytotoxicity. Potential applications include bioremediation and medical fields.

Radhika NP et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e15933

PubMed:

37215805

Acute effects of nitrate and breakfast on working memory, cerebral blood flow, arterial stiffness, and psychological factors in adolescents: Study protocol for a randomised crossover trial.

This study will explore if inorganic nitrate and breakfast can improve working memory, cerebral blood flow, arterial stiffness, and psychological outcomes in Swedish adolescents.

Regan C et al (2023).

PLoS One.

DOI:

10.1371/journal.pone.0285581

PubMed:

37205681

Summation of activation at the branch-stem transition of Mimosa pudica; a comparison with summation in cardiac tissue.

Mimosa pudica plants and rat heart cells show distinct electrical responses to different stimuli. Cooling affects specific branches, while heat affects the whole plant. Mechanical cutting activates the plant with a time delay, suggesting its role in propagating harmful stimuli.

de Bakker JMT and Coronel R (2023).

PLoS One.

DOI:

10.1371/journal.pone.0286103

PubMed:

37205655

Neocryptotanshinone ameliorates insufficient energy production in heart failure by targeting retinoid X receptor alpha.

A study explored the effects of neocryptotanshinone (NCTS) on energy metabolism to protect against heart failure after myocardial infarction (AMI) through the retinoid X receptor alpha (RXRα)/PPARα pathway. NCTS improved cardiac function and increased fatty acid oxidation and mitochondrial biogenesis.

Ma L et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.114868

PubMed:

37201263

Bilobalide Prevents Apoptosis and Improves Cardiac Function in Myocardial Infarction.

Bilobalide from Ginkgo biloba leaves has cardioprotective effects in myocardial infarction by reducing cardiomyocyte apoptosis and myocardial fibrosis via the inactivation of JNK/p38 MAPK signaling pathways. It may be an effective treatment.

Song W et al (2023).

Mol Biotechnol.

DOI:

10.1007/s12033-023-00753-8

PubMed:

37199885

Application of omics technology to investigate the mechanism underlying the role of San Hua Tang in regulating microglia polarization and blood-brain barrier protection following ischemic stroke.

Luo S et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.116640

PubMed:

37196812

Piperlongumine treatment impacts heart and liver development and causes developmental delay in zebrafish (Danio rerio) embryos.

Piperlongumine (PL) and piperine (PP) are alkaloids with anti-cancer potential. PL is highly toxic and affects heart development, while PP is safe. Careful strategies are needed when developing PL as a medicine.

Jeon HJ et al (2023).

Ecotoxicol Environ Saf.

DOI:

10.1016/j.ecoenv.2023.114995

PubMed:

37167734