Cardiology Studies

Implications of deltamethrin on hematology, cardiac pathology, and gene expression in Nile tilapia (Oreochromis niloticus) and its possible amelioration with Shatavari (Asparagus racemosus).

Shatavari extract protected Nile tilapia from heart damage caused by Deltamethrin pesticide. It restored blood parameters, reduced toxicity levels, and improved cardiac function through antioxidant and anti-apoptotic mechanisms.

Vineetha VP et al (2023).
Vet Res Commun.
PubMed:
37930611

Reducing myocardial infarction by combination of irisin and Dendrobium nobile Lindl through inhibiting nod-like receptor protein-3-related pyroptosis and activating PINK1/Parkin-mitophagy during aging.

Irisin/Dendrobium nobile Lindl combination therapy protects against myocardial IR injury in aged rats by suppressing pyroptosis and enhancing mitophagy. This therapy improves cardiac function, decreases LDH and cTn-I levels, and reduces inflammation. Further studies needed for potential use in aging-related heart disease.

Ding C and Zhang C (2023).
Chin J Physiol.
PubMed:
37929346

Utilization of Quince (Cydonia oblonga) Peel and Exploration of Its Metabolite Profiling and Cardioprotective Potential Against Doxorubicin-Induced Cardiotoxicity in Wistar Rats.

Researchers investigated the potential of quince peel as a sustainable food source. They found that a hydroethanolic extract of quince peel exhibited high antioxidant activity and protected against doxorubicin-induced cardiotoxicity in rats. This suggests that quince peel could have cardioprotective effects.

Hanan E et al (2023).
ACS Omega.
PubMed:
37929101

De novo assembly of Iron-Heart Cunninghamia lanceolata transcriptome and EST-SSR marker development for genetic diversity analysis.

Scientists sequenced the transcriptome of Iron-Heart Cunninghamia lanceolata, a Chinese fir relative with potential breeding traits. They obtained genetic information, identified molecular markers, and developed SSR primers for breeding, genetic analysis, and conservation efforts.

Liu S et al (2023).
PLoS One.
PubMed:
37917740

CARDIOPROTECTIVE EFFECT OF DICHLOROMETHANE VALERIAN (VALERIANA OFFICINALIS) EXTRACT ON ISCHEMIA-REPERFUSION-INDUCED CARDIAC INJURIES IN RATS.

Valepotriate in valerian has potent antioxidant properties and is beneficial for various cardiovascular conditions.

Sedighi M et al (2023).
Acta Endocrinol (Buchar).
PubMed:
37908890

Cardioprotective Role of Tinospora cordifolia against Trimethylamine-NOxide and Glucose Induced Stress in Rat Cardiomyocytes.

Researchers investigated the relationship between gut microbiota, metabolites, and cardiac contractility in type 2 diabetes. They found that dysbiosis of gut microbiota and secretion of metabolites can directly harm cardiac contractility. This information is important for understanding the causes of diabetic cardiomyopathy and improving patient safety.

Singhal S and Rani V (2023).
Cardiovasc Hematol Agents Med Chem.
PubMed:
37907489

Brassica oleracea L. extract ameliorates isoproterenol- induced myocardial injury by regulating HIF-1α-mediated glycolysis.

Researchers analyzed the constituents of Brassica oleracea L. leaf extract (BOE) and found that it can inhibit cardiac cell hypertrophy, reduce harmful substances in the body, increase mitochondrial function, and decrease apoptosis-related proteins. This suggests that BOE may protect against myocardial cell injury.

Luan H et al (2023).
Fitoterapia.
PubMed:
37907131

Mechanism of Artemisia annua L. in the treatment of acute myocardial infarction: network pharmacology, molecular docking and in vivo validation.

This study used network pharmacology, molecular docking, and in vivo experiments to investigate the potential of Artemisia annua in treating acute myocardial infarction. It identified key targets and pathways and demonstrated the extract's positive effects on ventricular function and reducing fibrosis.

Liang D et al (2023).
Mol Divers.
PubMed:
37898972