Cardiology Studies

Protective effect of Nardostachys jatamansi extract against lithium-pilocarpine-induced spontaneous recurrent seizures and associated cardiac irregularities in a rat model.

The plant Nardostachys jatamansi is commonly used in traditional medicine to treat epilepsy and cardiovascular issues. Its underground parts are specifically used for this purpose.

Sharma S et al (2023).
J Ethnopharmacol.
PubMed:
36813245

The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial.

Sabbaghzadegan S et al (2023).
Phytother Res.
PubMed:
36808781

Dark Sweet Cherry (Prunus avium) Supplementation Reduced Blood Pressure and Pro-Inflammatory Interferon Gamma (IFNγ) in Obese Adults without Affecting Lipid Profile, Glucose Levels and Liver Enzymes.

This study found that consuming dark sweet cherries may lower blood pressure and reduce inflammation in obese adults.

Arbizu S et al (2023).
Nutrients.
PubMed:
36771387

Multitarget Potential of Phytochemicals from Traditional Medicinal Tree, Terminalia arjuna (Roxb. ex DC.) Wight & Arnot as Potential Medicaments for Cardiovascular Disease: An In-Silico Approach.

Kumar V et al (2023).
Molecules.
PubMed:
36770716

Combination of Radix Astragali and Safflower Promotes Angiogenesis in Rats with Ischemic Stroke via Silencing PTGS2.

Radix astragali-safflower (AS) has been used for centuries in China to treat patients with ischemic stroke (IS). In this study, network pharmacology was used to uncover the mechanism of AS in treating IS. AS was shown to promote angiogenesis, which was associated with PTGS2 silence. Middle cerebral artery occlusion/reperfusion (MCAO/R) model rats were then treated with AS and showed improved cerebral infarct volume, neurological and histopathological damage, inhibition of cell apoptosis, and increased levels of PDGF-BB, EPO, and TGF-β1. AS was found to promote angiogenesis in MCAO/R rats by reversing the down-regulation of VEGF and promoting the expression of CD31. The protective mechanism of AS for IS involves PTGS2 silence.

Xu S et al (2023).
Int J Mol Sci.
PubMed:
36768450