Cardiology Studies

Elucidating the chemical interaction effects of herb pair Danshen-Chuanxiong and its anti-ischemic stroke activities evaluation.

This study investigates the combined effect of Salvia miltiorrhiza and Ligusticum chuanxiong in treating ischemic stroke. Understanding this synergy can help make better decisions in using traditional Chinese medicines for stroke treatment.

Pang HQ et al (2024).
J Ethnopharmacol.
PubMed:
37597675

An optimized machine learning method for predicting wogonin therapy for the treatment of pulmonary hypertension.

Wogonin, derived from Scutellaria baicalensis Georgi, can mitigate the progression of pulmonary hypertension (PH) in mice. A noninvasive prediction method using feature selection (BSCDWOA-KELM) can accurately screen key indicators in PH datasets. This method can be used to predict wogonin therapy for PH.

Li Y et al (2023).
Comput Biol Med.
PubMed:
37591162

Effects of aurantiamide on a rat model of renovascular arterial hypertension.

Asperglaucide, found in purslane, lowered blood pressure, improved vascular function, and increased eNOS expression, suggesting it may be a potential anti-hypertensive agent.

Aslan M et al (2023).
Pflugers Arch.
PubMed:
37582694

Olea europaea L. leaf extract mitigates oxidative and histological damage in rat heart tissue exposed to combined noise and toluene: An experimental study.

This study found that simultaneous exposure to toluene and noise altered cholesterol, triglycerides, and enzyme levels in rat hearts. Treatment with olive leaf extract helped mitigate these effects.

Ben Attia T et al (2023).
Saudi Pharm J.
PubMed:
37576861

Extract of Chenopodium album lowers blood pressure in rats through endothelium-dependent and -independent vasorelaxation.

This study examines the potential of Chenopodium album to lower blood pressure, based on its traditional usage. Relevant for managing hypertension.

Javed A et al (2023).
Ann Pharm Fr.
PubMed:
37572955

The effect of microencapsulated watermelon rind (Citrullus lanatus) and beetroot (Beta vulgaris L.) ingestion on ischemia/reperfusion-induced endothelial dysfunction: a randomised clinical trial.

This study looked at the effects of watermelon rind and beetroot on endothelial dysfunction caused by ischemia/reperfusion injury. They found that both watermelon rind and beetroot supplementation improved macrovascular function and increased plasma markers of vascular health. Co-ingestion of watermelon and beetroot did not offer additional benefits.

Volino-Souza M et al (2023).
Food Funct.
PubMed:
37561087

Associations Between Monthly Cannabis Use and Myocardial Infarction in Middle-Aged Adults: NHANES 2009 to 2018, Corroon et al.

This study analyzed data from middle-aged adults and found that a history of monthly cannabis use >1 year before a heart attack was not associated with a heart attack, except when cannabis was not used within the past month.

Corroon J et al (2023).
Am J Cardiol.
PubMed:
37556891

Ginkgo biloba extract (EGb-761) confers neuroprotection against ischemic stroke by augmenting autophagic/lysosomal signaling pathway.

Ginkgo biloba extract (EGb-761) promotes autophagic/lysosomal signaling in neurons and reduces infarction size, neurological deficits, and neuron death in ischemic stroke. It could be a potential new treatment target.

Zang R et al (2023).
J Neuroimmunol.
PubMed:
37536050