Cardiology Studies

Potentilla reptans L. preconditioning regulates H19 and MIAT long noncoding RNAs in H9C2 myoblasts Ischemia/Reperfusion model.

PEF from P. reptans root improved cell viability and reduced apoptosis in H9C2 myoblasts under I/R conditions by regulating lncRNAs H19 and MIAT. Cardioprotective potential.

Mirzaei H et al (2023).
BMC Complement Med Ther.
PubMed:
37525174

Of mixed vegetables and cardiac arrhythmias - Digitalis purpurea confused with Borago officinalis: A case series of accidental digitoxin intoxications.

Two women ate vegetables from their garden, thinking one was borage but accidentally ate foxglove. They experienced severe symptoms and elevated digitoxin levels. Plant misclassifications can be dangerous.

Iraci F et al (2023).
J Cardiol Cases.
PubMed:
37521578

Phenolics Extracted from Jasminum sambac Mitigates Diabetic Cardiomyopathy by Modulating Oxidative Stress, Apoptotic Mediators and the Nfr-2/HO-1 Pathway in Alloxan-Induced Diabetic Rats.

Phenolic acids extracted from leaves improved cardiac function and reduced complications of diabetes-induced cardiomyopathy in rats, suggesting potential therapeutic effects against diabetes-related heart problems.

Umar U et al (2023).
Molecules.
PubMed:
37513325

Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial.

Study tested whether beetroot juice (BRJ) could lower blood pressure in adults with ADPKD. Results showed BRJ increased nitric oxide, reducing clinic blood pressure.

Sagar PS et al (2023).
Trials.
PubMed:
37507763

Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway.

Arjunolic acid is a natural compound found in a plant called Combretaceae. It has cardiovascular protective effects, but we don't know how it works exactly.

Hasan MM et al (2023).
Pharm Biol.
PubMed:
37497554

Gram-Scale Total Synthesis of TAB with Cardioprotective Activity and the Structure-Activity Relationship of Its Analogs.

Traditional Chinese medicine, specifically Tournefolic acid B, has shown significant cardio-protective effects against myocardial ischemia reperfusion injury. Gram-scale synthesis method of TAB was established, and analogs with similar activity were synthesized, showing potential as a novel cardioprotective agent.

Sun Z et al (2023).
Molecules.
PubMed:
37446862