Researchers investigated the effects of Licochalcone A (LCA) on myocardial ischemia-reperfusion (I/R) injury. LCA demonstrated cardioprotective effects by inhibiting ferroptosis and reducing markers of damage. This suggests a potential new treatment strategy for I/R injury.
Ruscogenin, extracted from Ophiopogon japonicus, has shown potential in reducing cerebral ischemia-reperfusion injury and acute lung injury. However, its chronopharmacological effects have yet to be determined.
Ginkgo biloba extract (EGb) has beneficial effects on ischemic stroke by reducing neurobehavioral scores, infarct volume, inflammation, and increasing Treg cells. EGb can be used as part of future stroke therapy.
Potentilla reptans root extract shows potential for protecting the brain and reducing beta-amyloid in a rat model, indicating possible benefits for stroke and neurodegenerative diseases.
L. extract and kaempferol protected rat hearts against ISO-induced heart damage. They reduced cholesterol and triglycerides and increased HDL levels. They also improved heart antioxidant activity and reduced inflammation, suggesting they could prevent cardiovascular disorders.
Gut bacteria imbalance causes intestinal and other diseases. Specific metabolites (like bile acids and trimethylamine) play a role. Elevated levels of oxidized trimethylamine link to cardiovascular disease. Herbal medicines and prebiotics could help restore balance and improve health.
The study analyzed patients with asymptomatic atherosclerosis and high arterial stiffness. Triple combination therapy with γ-linolenic acid, Vitis vinifera extract, and acetyl-L-carnitine reduced arterial stiffness in both sexes. Changes in blood glucose and lipid levels were not observed.
Garlic has numerous health benefits including antioxidant, antifungal, antibacterial, antidiabetic, anti-inflammatory, anticancer, and antiviral effects. This study provides a mini-review on the chemistry and pharmacology of garlic for treating cardiovascular/heart-related diseases.