E. globulus leaf EO exhibits anti-inflammatory effects by regulating GSDMD-mediated pyroptosis, thereby alleviating neurological impairment and neuroinflammation in experimental stroke mice.

Researchers studied the chemical composition and anti-inflammatory properties of Eucalyptus globulus leaf essential oil from China. This plant is widely used in alternative medicine in developing countries.

Wang D et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117367

PubMed:

38380569

Valerenic acid attenuates pathological myocardial hypertrophy by promoting the utilization of multiple substrates in the mitochondrial energy metabolism.

Researchers studied valerenic acid (VA) in Valeriana officinalis L. for its potential in treating pathological myocardial hypertrophy (PMH) with positive results. VA's regulatory effect on the cardiovascular system could provide new treatment options for cardiac diseases.

Liu T et al (2024).

J Adv Res.

DOI:

10.1016/j.jare.2024.02.008

PubMed:

38373650

Anji white tea relaxes precontracted arteries, represses voltage-gated Ca(2+) channels and voltage-gated K(+) channels in the arterial smooth muscle cells: Comparison with green tea main component (-)-epigallocatechin gallate.

Researchers studied the vascular effects of Anji white tea, a popular green tea rich in EGCG, to better understand its potential benefits for cardiovascular health.

Xu X et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117855

PubMed:

38346524

Application and mechanisms of Sanhua Decoction in the treatment of cerebral ischemia-reperfusion injury.

Sanhua Decoction, a traditional Chinese medicinal formulation, shows potential in treating cerebral ischemia-reperfusion injury. It acts through antioxidant, anti-inflammatory, and neurotransmitter regulatory pathways to protect nerve cells and reduce cerebral edema. Studying its mechanisms can improve understanding and future clinical application.

Wang YK et al (2024).

World J Clin Cases.

DOI:

10.12998/wjcc.v12.i4.688

PubMed:

38322692

"Every beet you take": lowering systolic blood pressure and improving vascular function/exercise capacity via the dietary nitrate-nitrite-NO pathway in patients with COPD.

Webb AJ et al (2024).

Eur Respir J.

DOI:

10.1183/13993003.02238-2023

PubMed:

38302179

Effect of Syzygium cumini on Oxidative Stress Induced Cardiac Cellular Anomalies.

Researchers found that Syzygium cumini (Black berry) could be a natural way to protect the heart against Doxorubicin-induced damage. Its antioxidants and anti-inflammatory properties make it a promising option for cardio-oncological therapies.

Bhadana R and Rani V (2024).

Cardiovasc Hematol Agents Med Chem.

DOI:

10.2174/0118715257273859231211112731

PubMed:

38299280

Synergistic effects and molecular mechanisms of DL-3-n-butylphthalide combined with dual antiplatelet therapy in acute ischemic stroke.

Combining DL-3-n-butylphthalide (NBP) and dual antiplatelet therapy (DAPT) improves acute ischemic stroke in rats. It reduces neurological deficits, infarct area, and inflammation by suppressing the pyroptosis-inflammation pathway in brain tissues, especially in microglial cells.

Du Y et al (2024).

Int Immunopharmacol.

DOI:

10.1016/j.intimp.2024.111592

PubMed:

38295546

Triptolide attenuates cardiac remodeling by inhibiting pyroptosis and EndMT via modulating USP14/Keap1/Nrf2 pathway.

Researchers investigated the effects of triptolide on cardiac remodeling, a common feature in heart diseases. They found that triptolide can inhibit cardiac hypertrophy and fibrosis, suggesting its potential as a treatment option.

Ba L et al (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e24010

PubMed:

38293551