Cardiology Studies

Aphid resistance segregates independently of cardiac glycoside and glucosinolate content in an Erysimum cheiranthoides (wormseed wallflower) F2 population.

Scientists studied two wormseed wallflower plant isolates and found differences in their defensive metabolites and resistance to aphids. Genetic factors affect metabolite production, but other unknown processes contribute to aphid resistance.

Mirzaei M et al (2024).
bioRxiv.
PubMed:
38293015

Effects of scutellarin on the mechanism of cardiovascular diseases: a review.

Researchers studied scutellarin, a compound found in a plant, for its potential to treat heart diseases. Finding safe and effective treatments for cardiovascular diseases is crucial due to their increasing prevalence and risks of side effects from current medications.

Zhang X et al (2024).
Front Pharmacol.
PubMed:
38259289

The Cardioprotective Properties of Selected Nuts: Their Functional Ingredients and Molecular Mechanisms.

This review discusses the nutritional benefits of nuts and their potential role in preventing and treating cardiovascular diseases. Almonds, walnuts, and pistachios are found to be the most beneficial due to their high content of bioactive compounds with cardioprotective properties.

Olas B et al (2024).
Foods.
PubMed:
38254543

Wogonin alleviates NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating AMPK/SIRT1.

Wogonin, a natural flavonoid, protects against cerebral ischemia-reperfusion (IR) injury by reducing inflammation through the AMPK/SIRT1/NLRP3 inflammasome pathway. It improves neurological function and reduces brain damage.

Cheng Z et al (2024).
Brain Res Bull.
PubMed:
38253131

Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.

Safranal, an active compound in saffron, reduces brain damage after ischemic stroke (IS) by reducing oxidative stress. It promotes neuron survival, stimulates neurogenesis, induces angiogenesis, and increases SIRT1 expression. Silencing SIRT1 reverses these effects. Safranal shows promise for restoring neural function after IS.

He F et al (2023).
Exp Ther Med.
PubMed:
38234630

Cardiac glycosides protect wormseed wallflower (Erysimum cheiranthoides) against some, but not all, glucosinolate-adapted herbivores.

Researchers studied how the evolution of a new defensive compound in a plant affects its interactions with herbivores. They identified enzymes involved in the production of the compound and found that it effectively defended against some, but not all, specialist herbivores. This research helps understand the chemical arms race between plants and insects.

Younkin GC et al (2024).
New Phytol.
PubMed:
38229566

Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats.

This study showed that the herb () has potent antioxidant activity and can reduce oxidative stress in the heart. It protected against isoprenaline-induced heart injury and could be a potential alternative therapy for cardiovascular diseases.

Hosseini A et al (2023).
Front Pharmacol.
PubMed:
38223198

Hydroxysafflor Yellow A and Tenuigenin Exhibit Neuroprotection Effects Against Focal Cerebral Ischemia Via Differential Regulation of JAK2/STAT3 and SOCS3 Signaling Interaction.

Combining natural compounds in Chinese medicine, hydroxysafflor yellow A (HSYA) and tenuigenin (TEN), shows promise in treating ischemic stroke by improving various aspects of brain function and suppressing cell apoptosis. This combination modulates signaling pathways, leading to synergistic effects against stroke.

Yu L et al (2024).
Mol Neurobiol.
PubMed:
38214838