Onopordum acanthium L. extract attenuates pancreatic β-Cells and cardiac inflammation in streptozocin-induced diabetic rats.

Sharef AY et al (2023).

PLoS One.

DOI:

10.1371/journal.pone.0280464

PubMed:

36696433

The Carthamus tinctorius L. and Lepidium apetalum Willd. Drug Pair Inhibits EndMT through the TGFβ1/Snail Signaling Pathway in the Treatment of Myocardial Fibrosis.

Zhou Z et al (2023).

Evid Based Complement Alternat Med.

DOI:

10.1155/2023/6018375

PubMed:

36686974

Crocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I.

Researchers have discovered that crocetin, a natural antioxidant found in saffron, can counteract the process of programmed cell death, known as parthanatos, during an ischemic stroke. They found that crocetin reduces the production of reactive oxygen species and poly (ADP-ribose), both associated with parthanatos, at early stages of the process, and prevents the degradation of hexokinase-I, which helps maintain mitochondrial function, at later stages. The study suggests that crocetin may be a potential drug candidate for preventing and treating ischemic stroke.

Wu H et al (2023).

Cell Death Dis.

DOI:

10.1038/s41419-023-05581-x

PubMed:

36681688

Terminalia arjuna, a Cardioprotective Herbal Medicine-Relevancy in the Modern Era of Pharmaceuticals and Green Nanomedicine-A Review.

Ramesh P and Palaniappan A (2023).

Pharmaceuticals (Basel).

DOI:

10.3390/ph16010126

PubMed:

36678623

A Nutraceutical Containing Chlorogenic Acid and Luteolin Improves Cardiometabolic Parameters in Subjects with Pre-Obesity: A 6-Month Randomized, Double-Blind, Placebo-Controlled Study.

A study found that Altilix, a nutraceutical containing chlorogenic acid and luteolin, improved weight, glucose metabolism, lipid profile, hepatic functionality, and cardiovascular health in pre-obesity subjects.

Terzo S et al (2023).

Nutrients.

DOI:

10.3390/nu15020462

PubMed:

36678333

Consumption of Eggs Alone or Enriched with Annatto (Bixa orellana L.) Does Not Increase Cardiovascular Risk in Healthy Adults-A Randomized Clinical Trial, the Eggant Study.

This study found that consuming two eggs a day or two eggs enriched with Annatto for eight weeks did not have adverse effects on cardiovascular risk markers in healthy adults.

Galvis Y et al (2023).

Nutrients.

DOI:

10.3390/nu15020369

PubMed:

36678239

Dihydromyricetin Attenuates Diabetic Cardiomyopathy by Inhibiting Oxidative Stress, Inflammation and Necroptosis via Sirtuin 3 Activation.

Chen Y et al (2023).

Antioxidants (Basel).

DOI:

10.3390/antiox12010200

PubMed:

36671063

Swietenine Alleviates Vascular Remodeling by Enhancing Mitophagy of Pulmonary Arterial Smooth Muscle Cells in Experimental Pulmonary Hypertension.

Chu C et al (2023).

Can J Cardiol.

DOI:

10.1016/j.cjca.2023.01.003

PubMed:

36641049