GeoBotanical: Cardiology Studies

385.

Role of a Novel Silver Fir (Abies alba) Extract, Abigenol(®)/AlbiPhenol(®), in Modulating Cardiovascular Disorders: Key Factors.

Cardiology Abies alba

Leone K et al (2022).; Antioxidants (Basel).
DOI:: 10.3390/antiox11040618
PubMed:: 35453303

386.

Cardio-protective effects of terminalia catappa leaves and terminalia chebula fruit extract in doxorubicin-induced cardiomyopathy in rats.

Cardiology Terminalia catappa

Manikandan R et al (2022).; Biomarkers.
DOI:: 10.1080/1354750X.2022.2064550
PubMed:: 35400254

387.

Using Network Pharmacology to Explore the Mechanism of Panax notoginseng in the Treatment of Myocardial Fibrosis.

Cardiology Panax notoginseng

Han J et al (2022).; J Diabetes Res.
DOI:: 10.1155/2022/8895950
PubMed:: 35372585

388.

Smilax glabra Roxb. flavonoids protect against pathological cardiac hypertrophy by inhibiting the Raf/MEK/ERK pathway: In vivo and in vitro studies.

Cardiology Phytochemistry Smilax glabra

Fu D et al (2022).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2022.115213
PubMed:: 35331878

389.

Cardioprotective and Antioxidant Efficiency of Balanites aegyptiaca Extract Against Doxorubicin(®) Complication.

Cardiology Immunology Balanites aegyptiaca

F Gomaa H et al (2022).; Pak J Biol Sci.
DOI:: 10.3923/pjbs.2022.270.281
PubMed:: 35234018

390.

Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway.

Geraniin, a polyphenol, was studied for its potential to protect against cerebral ischemia/reperfusion (I/R) injury. The study used both in vivo and in vitro models to evaluate the neuroprotective effect of geraniin. Geraniin showed a significant reduction in infarct volume, decreased neurological deficit scores, and reduced cell apoptosis. It also increased the activity of superoxide dismutase (SOD) and decreased the activity of lactate dehydrogenase (LDH) and malondialdehyde (MDA), suggesting its antioxidant capacity. Additionally, geraniin increased Nrf2/HO-1 protein expression in vivo and in vitro, indicating an association with the protective effect against I/R injury. Geraniin shows promise as a potential treatment for ischemic stroke.

Cardiology Immunology Neuroscience Phyllanthus amarus

Yang Y et al (2022).; Oxid Med Cell Longev.
DOI:: 10.1155/2022/2152746
PubMed:: 35222793

391.

Inhibition of thioredoxin-interacting protein may enhance the therapeutic effect of dehydrocostus lactone in cardiomyocytes under doxorubicin stimulation via the inhibition of the inflammatory response.

Cardiology Immunology Saussurea lappa

Zhang X, Chu C and Huang Y (2022).; Exp Ther Med.
DOI:: 10.3892/etm.2022.11150
PubMed:: 35222703

392.

Extracts of Bauhinia Championii Alleviate Acute Neuronal Injury After Ischemic Reperfusion by Improving Endoplasmic Reticulum Stress-Mediated Neuronal Apoptosis.

Scientists investigated whether extracts from the Bauhinia championii plant could prevent neuronal injury caused by cerebral ischemia/reperfusion (I/R), which currently lacks effective remedies and can result in lethal injury. BCEs have previously shown anti-oxidative and anti-hypoxia properties. The study's findings suggest that BCE may be a potential treatment for I/R-induced neuronal injury.

Cardiology Neuroscience Bauhinia championii

Huang M et al (2022).; Curr Med Sci.
DOI:: 10.1007/s11596-022-2525-4
PubMed:: 35220494