Aqueous extract of Solanum nigrum attenuates Angiotensin-II induced cardiac hypertrophy and improves cardiac function by repressing protein kinase C-ζ to restore HSF2 deSUMOlyation and Mel-18-IGF-IIR signaling suppression.

Lin HJ et al (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2021.114728

PubMed:

34634367

Cardioprotective Effects of Oroxylum indicum Extract Against Doxorubicin and Cyclophosphamide-Induced Cardiotoxicity.

Pondugula SR et al (2022).

Cardiovasc Toxicol.

DOI:

10.1007/s12012-021-09701-x

PubMed:

34623620

Protective Effects of Caesalpinia sappan Linn. and Its Bioactive Compounds on Cardiovascular Organs.

Syamsunarno MRA, Safitri R and Kamisah Y (2021).

Front Pharmacol.

DOI:

10.3389/fphar.2021.725745

PubMed:

34603037

Neuroprotective effect of wild lowbush blueberry (Vaccinium angustifolium) on global cerebral ischemia/reperfusion injury in rats: Downregulation of iNOS/TNF-α and upregulation of miR-146a/miR-21 expression.

A study investigated the neuroprotective effect of wild lowbush blueberry on rats with induced cerebral ischemia and reperfusion. The rats were injected with BBE for 14 days and several parameters were measured. Results showed that BBE significantly decreased oxidative stress levels and increased antioxidant power levels in the hippocampus and serum, while also modulating neuroinflammatory cascades and protecting neurons against ischemic death. The study suggests that BBE may have potent neuroprotective efficacy against cerebral ischemia and reperfusion.

Moradi Z et al (2021).

Phytother Res.

DOI:

10.1002/ptr.7296

PubMed:

34580912

Jasminum sambac: A Potential Candidate for Drug Development to Cure Cardiovascular Ailments.

Khan IA et al (2021).

Molecules.

DOI:

10.3390/molecules26185664

PubMed:

34577135

Uncovering the molecular mechanisms of Ilex pubescens against myocardial ischemia-reperfusion injury using network pharmacology analysis and experimental pharmacology.

Zheng Y et al (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2021.114611

PubMed:

34537280

Protective mechanism of Erigeron breviscapus injection on blood-brain barrier injury induced by cerebral ischemia in rats.

Liu G et al (2021).

Sci Rep.

DOI:

10.1038/s41598-021-97908-x

PubMed:

34531475

Ischemic Stroke and Provoked Seizure as a Manifestation of Brugmansia suaveolens (Angel's Trumpet) Acute Intoxication: A Detailed Clinical, Electroencephalogram, and Magnetic Resonance Imaging Description and 5-Month Follow-up.

Colosimo E et al (2021).

Clin Neuropharmacol.

DOI:

10.1097/WNF.0000000000000478

PubMed:

34516441