The effect of Nigella sativa on the risk of mortality in patients with COVID-19: A systematic review and meta-analysis of randomized trials.
- Kow CS, Ramachandram DS and Hasan SS (2023).
- Phytother Res.
- DOI:
- 10.1002/ptr.7743
- PubMed:
- 36757063
This study reviewed the potential effects of Thymus vulgaris (TvL) and its active compounds (thymol and carvacrol) on COVID-19. SARS-CoV-2 causes COVID-19 by interacting with the ACE2 receptor and causing tissue damage. TvL has antimicrobial, antiseptic, and antiviral properties, and thymol and carvacrol have anti-inflammatory, antioxidant, and immunomodulatory properties. The study suggests that TvL and its active compounds may have beneficial effects in treating COVID-19, but further research is needed.
Researchers synthesized a novel ligand and used it to create nanocomplexes with chromium and copper in an environmentally friendly manner. They analyzed the structure and properties of the complexes using various techniques and found them to be more stable than the free ligand. The chromium nanocomplex showed strong antitumor activity after being heated, while the copper nanocomplex exhibited good DNA cleavage. Molecular docking was used to study the potential of the complexes to bind to liver cancer and COVID-19 proteins.
Researchers used computer analysis to search for potential COVID-19 treatments. They focused on a chemical found in essential oils. This approach could lead to the discovery of new antiviral drugs.
Researchers tested a collection of natural product extracts from popular botanical dietary supplements for their efficacy against SARS-CoV-2, the virus causing COVID-19. Out of 1867 extracts and 18 compounds, 310 extracts from 188 species were identified as having ≥ 50% viral entry inhibition activity at 20 µg/mL, with three extracts showing potent antiviral activity against both pseudotyped variants and infectious SARS-CoV-2. Two of these extracts were from Solidago altissima L. (Asteraceae) flowers and Pteridium aquilinum (L.) Kuhn (Dennstaedtiaceae) rhizomes. These findings could have important implications for the development of treatments for COVID-19 using botanical dietary supplements.
Complications from COVID-19 have been well-documented, but less attention has been given to post-COVID complications which can last for more than 6 months. Available drugs tackle the issue but new interventions are required. An edible plant, Solanum nigrum, shows potential in treating COVID-19 symptoms. It demonstrates anti-inflammatory, immunomodulatory, and antiviral action to treat the infection and its post-complications, protecting various organs. Further experiments are needed to validate the hypothesis.
This study explores the potential of Traditional Arabic or Islamic medicinal plants as adjuvant therapy for COVID-19. Six medicinal plants with antiviral and immunomodulatory properties were studied, suggesting they could be used to control symptoms and possibly lead to a COVID-19 medicinal synthesis. However, further evaluation is advised before using these plants as therapy. No evidence-based medication to combat COVID-19 currently exists despite multiple vaccine strategies.