This medical abstract discusses the need for a natural drug to treat or prevent COVID-19, as traditional drugs may have side effects and the virus may become resistant to them over time. There is currently no known treatment or prevention for the virus.
Researchers studied the leaves of the Ficus plant for potential compounds to inhibit the COVID-19 virus. They found that two compounds, quercetin 3,7-O-α-L-dirhamnoside and rutin, had strong binding abilities to the virus' main protease, similar to the current inhibitor, darunavir. This suggests that these compounds may have potential for the development of therapies against COVID-19.
The current self-management recommendations for COVID-19 involve rest, hydration, and the use of NSAIDs for high fever. Many patients may also use herbal medicines.
Despite global efforts, a specific therapy or vaccine against COVID-19 remains elusive. Prevention and intervention through isolation, hygiene measures, diagnosis, and treatment are the most effective ways to combat the virus. Health organizations and global care systems have screened available resources and recommended approved and proposed medications. The search for a targeted therapy or vaccine continues as the world battles this unprecedented enemy.
Nigella sativa seed and its active compounds have been historically recognized as an effective herbal panacea that can promote a healthy immune response and suppress chronic inflammation. Recent findings suggest that N. sativa could be a potential candidate in nutraceuticals to prevent and cure COVID-19. The review aims to revisit the pharmacological benefits of N. sativa seed and its active metabolites that could be a potential basis for developing a novel preventive and therapeutic strategy against COVID-19. Bioactive compounds of N. sativa seed, especially thymiquinone, α-hederin, and nigellidine, could be promising herbal drugs to combat COVID-19. Preclinical and clinical trials are required to investigate their efficacy and potency under specific pathophysiological conditions of COVID-19.
Scientists have identified 93 potential drug candidates from natural products such as medicinal plants and herbs that could effectively inhibit the coronavirus, including COVID-19. These candidates include pure compounds like Blancoxanthone and herbacetin, and extracts from plants like Artemisia annua and Tinospora cordifolia. The study suggests that natural products can be used as a source for potential drug discovery against COVID-19 and other respiratory viruses, including SARS and MERS-CoV. This provides a promising avenue for future research to develop effective treatments for the ongoing pandemic.
A review article suggests that natural products like plants and herbs could be used as potential treatments for COVID-19 based on their antiviral activities against other coronaviruses. The authors searched through multiple scientific databases and found that certain plants and herbs, such as Allium sativum, Zingiber officinale, and Glycyrrhiza glabra, have been shown to improve immune response and inhibit viral replication. The study also identified specific compounds, such as terpenoids and alkaloids, with promising effects against coronavirus targets like the S protein and viral enzymes. Overall, the article suggests that natural products could be used as preventive and therapeutic agents in the fight against COVID-19.