Diabetes Studies

The neuroprotective role of celastrol on hippocampus in diabetic rats by inflammation restraint, insulin signaling adjustment, Aβ reduction and synaptic plasticity alternation.

Celastrol from Tripterygium wilfordii protects diabetic rats against cognitive decline by improving insulin sensitivity, glucose tolerance, and reducing inflammation in the brain. Celastrol also promotes the synthesis of synaptic proteins, enhancing cognitive function.

DiabetesImmunologyNeuroscience Tripterygium wilfordii
Zhou Q et al (2024).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2024.117397
PubMed:
39232386

Ameliorative Effects of Essential Oils on Diabetes Mellitus: A Review.

Review of essential plant oils as potential herbal remedies for diabetes mellitus. EOs from 20 plants show anti-diabetic activity, with bioactive compounds like carvacrol and thymol inhibiting key enzymes. Promising for drug development.

Diabetes Nigella sativa
Barbhuiya PA et al (2024).
Curr Top Med Chem.
DOI:
10.2174/0115680266314922240822091215
PubMed:
39225203

Herbal medicine use and its impact on glycemic control among diabetes patients at governmental hospitals in Debre Berhan, Ethiopia: A cross-sectional study.

Study in Ethiopia shows diabetes patients using herbal medicine without medical advice. Impact on glycemic control unknown. Important for healthcare providers to understand patient behaviors for better management.

Diabetes Thymus schimperi
Lema GD et al (2024).
Metabol Open.
DOI:
10.1016/j.metop.2024.100311
PubMed:
39224191

Extraction, purification, chemical characterization, and in vitro hypoglycemic activity of polysaccharides derived from Rosa laevigata Michx.

TL;DR: Researchers optimized Rosa laevigata polysaccharide extraction with ultrasound-microwave method, studied its hypoglycemic properties. Results show potential as antioxidant/hypoglycemic drug due to improved glucose metabolism and oxidative stress reduction.

Diabetes Rosa laevigata
Chen S et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.135116
PubMed:
39208908

A Comparative Study on the Antidiabetic Activity, Cytotoxicity and Lipid Profile of Trichilia emetica Oils.

Study compared extraction methods of plant seed butter and aril oil for antidiabetic activity and cytotoxicity. Impact of extraction method on yield, activity, and lipid profile shown. Important for potential pharmaceutical development.

Diabetes Trichilia emetica
Aldholmi M et al (2024).
Plants (Basel).
DOI:
10.3390/plants13162234
PubMed:
39204668

Artemisia vulgaris Extract as a Novel Therapeutic Approach for Reversing Diabetic Cardiomyopathy in a Rat Model.

Methanolic extract of [plant] shows potential in reversing cardiac remodeling in diabetic cardiomyopathy, improving heart function and reducing side effects compared to current anti-hyperglycemic therapies.

CardiologyDiabetes Artemisia vulgaris
Liza et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17081046
PubMed:
39204151

Antidiabetic Potential of Abelmoschus manihot Flower Extract: In Vitro and Intracellular Studies.

Scientist's hangover shortcut: Medic flower extracts showed potent anti-diabetic effects by inhibiting enzymes, reducing oxidative stress, and protecting beta-cell function. Further research needed for potential diabetes management.

Diabetes Abelmoschus manihot
Wang SW et al (2024).
Medicina (Kaunas).
DOI:
10.3390/medicina60081211
PubMed:
39202492

Lycium chinense Mill Induces Anti-Obesity and Anti-Diabetic Effects In Vitro and In Vivo.

Mill extract (LCM) increases GLP-1 secretion, reduces lipid accumulation, promotes weight loss, improves glucose tolerance, and exhibits hepatoprotective properties in obesity and diabetes. Promising natural treatment option.

DiabetesObesity Lycium chinense
Jee W et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25168572
PubMed:
39201257
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