Diabetes Studies

Demonstration of the Protective Effect of Vinpocetine in Diabetic Cardiomyopathy.

Study on Vinpocetine's effects on diabetic cardiomyopathy showed it reduced heart damage, improved markers and structure. Vinpocetine may be a promising treatment for diabetic heart disease.

Erciyes D et al (2024).
J Clin Med.
PubMed:
39200779

Modulation of the Hyperglycemia Condition in Diabetic Lab Rats with Extracts of the Creole Jamaica Flower (Hibiscus sabdariffa L.) from the Morelia Region (Mexico).

Jamaica flower extracts from Morelia can lower blood glucose levels, improve lipid metabolism, and reduce insulin resistance in diabetic rats. They could be used as functional ingredients for managing diabetes.

Suárez-Diéguez T et al (2024).
Antioxidants (Basel).
PubMed:
39199254

The effect of Nigella sativa supplementation on glycemic status in adults: An updated systematic review and meta-analysis of randomized controlled trials.

Meta-analysis of 30 studies found Nigella sativa reduces blood sugar and HbA1c levels in adults. More research needed on dosage and duration for optimal results.

Shirvani S et al (2024).
Prostaglandins Other Lipid Mediat.
PubMed:
39181437

Exploring sesquiterpene lactone as a dual therapeutic agent for diabetes and oxidative stress: insights into PI3K/AKT modulation.

Artemisinin shows potential for anti-diabetic and antioxidant effects by targeting the PI3K/AKT pathway. It inhibits enzymes related to hyperglycaemia and exhibits antioxidant properties without toxicity in zebrafish models. This suggests a promising therapy for diabetes and oxidative stress.

Velumani K et al (2024).
3 Biotech.
PubMed:
39170770

Phyto-pharmacological and computational profiling of Bombax ceiba Linn. Leaves revealed pharmacological properties against oxidation, hyperglycemia, pain, and diarrhea.

Study isolated compounds from plant leaves, showing potential for antioxidant, analgesic, hypoglycemic, and anti-diarrheal properties. Further research needed for exact mechanisms, but promising for potential medicinal use.

Taher MA et al (2024).
Heliyon.
PubMed:
39170236

In vitro and in vivo evaluation of the diabetic wound healing properties of Saffron (Crocus Sativus L.) petals.

C. sativus petal extract promotes cell survival, migration, and angiogenesis, upregulating COL1A1 and VEGF. It accelerates wound closure, making it a potential herbal treatment for diabetic wounds.

Soheilifar MH et al (2024).
Sci Rep.
PubMed:
39169073

Multi-target anti-diabetic styrylpyrones from Phellinus igniarius: Inhibition of α-glucosidase, protein glycation, and oxidative stress.

Phellinus igniarius SY489 extract contains potent α-glucosidase inhibitors, including novel compounds, with potential as anti-diabetic drugs. Study suggests they interact with enzyme via mixed-type mechanism for promising drug development.

Yu G et al (2024).
Int J Biol Macromol.
PubMed:
39168223

The Anti-Diabetic Effects of Medicinal Plants Belonging to the Liliaceae Family: Potential Alpha Glucosidase Inhibitors.

Summary: Review of medicinal plants in the family for treating diabetes, particularly type II diabetes. Limited research, potential for new treatments targeting α-glucosidase enzyme. Important for discovering alternative therapies to manage diabetes.

Ramadaini T, Sumiwi SA and Febrina E (2024).
Drug Des Devel Ther.
PubMed:
39156483