Diabetes Studies

Therapeutic Effects of Nigella sativa Oil and Whole Seeds on STZ-Induced Diabetic Rats: A Biochemical and Immunohistochemical Study.

Researchers studied new therapies for Type II diabetes, aiming for higher efficacy, fewer side effects, and lower costs. This is important for improving patient outcomes and easing strain on healthcare systems globally.

AlSuhaymi N et al (2024).
Oxid Med Cell Longev.
PubMed:
39156220

Comprehensive metabolomics and chemometrics unravel potential anti-diabetic metabolites of pumpkin (Cucurbita pepo L.) fruits through UPLC-QqQ-MS and GC-MS analyses.

Scientists analyzed the chemical compounds in different parts of pumpkins and found they can help manage diabetes by inhibiting carbohydrase enzymes and promoting glucose uptake. Pumpkin is a potential functional food for diabetes management.

Abdelmonsef M et al (2024).
Food Res Int.
PubMed:
39147478

Integrative metabolomics and chemometrics depict the metabolic alterations of differently processed red kidney beans (Phaseolus vulgaris L.) and in relation to in-vitro anti-diabetic efficacy.

Study finds germination and cooking boost red kidney beans' antidiabetic properties, potentially aiding in diabetes management as a functional food.

Ghallab DS, Ghareeb DA and Goda DA (2024).
Food Res Int.
PubMed:
39147477

Dose-Dependent Attenuation of the Efficacy of Clitoria ternatea by Cobalt Oxide Nanoparticles Against Diabetes-Induced Cognitive Impairment.

Clitoria ternatea extract shows potential for treating diabetes-induced cognitive impairment. Cobalt oxide nanoparticles may improve brain drug delivery, but high doses are neurotoxic. Low doses show neuroprotective effects, warranting further study.

Satpathy B et al (2024).
Mol Neurobiol.
PubMed:
39143449

Nigella sativa L. and its bioactive and nutraceutical components in the management of diabetic peripheral neuropathy.

NS (black cumin) shows promise in reducing inflammation and oxidative stress associated with diabetic neuropathy. Research suggests potential benefits for treating complications of diabetes with fewer side effects.

Khodaie SA et al (2024).
Inflammopharmacology.
PubMed:
39143432

Chemical Profile and Potential Application of Agri-food Waste Products for Counteracting Diabetes Induced Neuropathy in Rats.

Extracts from okra, mulberry, and pomegranate leaves and peel help diabetic rats by reducing blood glucose, inflammation, and restoring brain health. Promising for treating diabetic neuropathy.

El Souda SS et al (2024).
Chem Biodivers.
PubMed:
39140441

Phytochemical screening, antioxidant, anti-diabetic, and anti-obesity activities, formulation, and characterization of a self-nanoemulsion system loaded with pomegranate (Punica granatum) seed oil.

Pomegranate seed oil self-nanoemulsifying system has potent antioxidant, anti-diabetic, and anti-lipase activities. Potential for oral medications in oxidative stress, diabetes, and obesity treatment.Enhanced drug formulations in terms of pharmacokinetics and pharmacodynamics.

Eid AM et al (2024).
Sci Rep.
PubMed:
39138188

Isolation of an α-glucosidase Inhibitor from Houttuynia cordata Thunb. and Its In vitro and In vivo Hypoglycemic Bioactivity.

Researchers isolated neochlorogenic acid from Houttuynia cordata Thunb., showing potential as a natural α-glucosidase inhibitor to lower blood glucose levels. This study lays the groundwork for developing new hypoglycemic treatments.

Cao P et al (2024).
Plant Foods Hum Nutr.
PubMed:
39133356