Diabetes Studies

Comparative Investigation of Chemical Constituents of Kernels, Leaves, Husk, and Bark of Juglans regia L., Using HPLC-DAD-ESI-MS/MS Analysis and Evaluation of Their Antioxidant, Antidiabetic, and Anti-Inflammatory Activities.

Bourais I et al (2022).
Molecules.
PubMed:
36558122

Attenuation of hyperglycemia-associated dyslipidemic, oxidative, cognitive, and inflammatory crises via modulation of neuronal ChEs/NF-κB/COX-2/NOx, and hepatorenal functional deficits by the Tridax procumbens extract.

A study evaluated the effects of Tridax procumbens (cotton buttons) extract on rats with induced type 2 diabetes. The extract improved fasting blood glucose levels, insulin levels, dyslipidemia, and antioxidant status while decreasing proinflammatory mediators. The most abundant bioactive compounds identified were isorhamnetin, bixin, and lupeol. The study shows promise for TPME as an alternative therapeutic option for managing diabetic complications.

Hogan IA et al (2023).
Biomed Pharmacother.
PubMed:
36525818