Endocrinology Studies

Phytochemicals-based investigation of Rubia cordifolia pharmacological potential against letrozole-induced polycystic ovarian syndrome in female adult rats: In vitro, in vivo and mechanistic approach.

Study formulated and tested a plant-based extract in PCOS-induced rats. Extract improved ovulation, hormone levels, liver function, and inflammation in ovaries. Potential treatment for PCOS.

Zhang J et al (2024).
Heliyon.
PubMed:
39108850

Treatment of D-galactose-induced rat polycystic ovarian condition using Lepidium sativum and secondary antibodies.

Scientists studied the causes and treatment of PCOS, a common hormonal disorder in women. Understanding this can lead to improved management and potential breakthroughs in treatment.

Alharbi Y, Alkhail AA and Zaki AK (2024).
J Adv Vet Anim Res.
PubMed:
39101077

Syzygium malaccense leaves methanol extract modulate some biochemical and inflammatory markers and prostate histology of testosterone-estradiol valerate induced benign prostatic hyperplasia in rats.

Methanol leaf extract may have potential in treating BPH by affecting testosterone and estradiol levels in rats. Further research needed for human application.

Achi NK et al (2024).
Avicenna J Phytomed.
PubMed:
39086866

Ageratum conyzoides Extract Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia via Inhibiting Proliferation, Inflammation of Prostates, and Induction of Apoptosis in Rats.

Standardized ethanolic extract of has shown potential as a phytotherapeutic agent for treating benign prostatic hyperplasia (BPH) in rats, with promising effects on prostate weight, androgen levels, and apoptotic signals. This research highlights the potential of as an alternative remedy for BPH.

Chung EH et al (2024).
Nutrients.
PubMed:
39064710

Effect of cinnamon as a Chinese herbal medicine on markers of cardiovascular risk in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials.

Study found that cinnamon supplementation can improve cardiovascular risk markers in women with PCOS. Cinnamon's anti-inflammatory and insulin-sensitizing properties make it a potential therapeutic agent for PCOS-related cardiovascular complications.

Xiaomei Z and Xiaoyan F (2024).
Eur J Obstet Gynecol Reprod Biol.
PubMed:
39053085

Linum usitatissimum Delivery over Chitosan Nanobiopolymer: Enhanced Effects on Polycystic Ovary Syndrome Condition.

Chitosan nanoparticles loaded with flaxseed extract showed improved stability and bioavailability. In a study on female rats with PCOS, CHIT-FSE had the best results in controlling hormonal and biochemical markers. Supporting phytomolecules on chitosan can enhance their therapeutic effectiveness.

Bayrami A et al (2024).
IET Nanobiotechnol.
PubMed:
39050969

Evaluating the role of soil EPS in modifying the toxicity potential of the mixture of polystyrene nanoplastics and xenoestrogen, Bisphenol A (BPA) in Allium cepa L.

Study examined combined effects of BPA and PSNPs on onion root cells. Aminated PSNPs + BPA most toxic. EPS reduced toxicity. Important for understanding impact of emerging pollutants on plants.

Giri S et al (2024).
J Hazard Mater.
PubMed:
39047567

Development of Daruharidra (Berberis aristata) Based Biogenic Cadmium Sulfide Nanoparticles: Their Implementation as Antibacterial and Novel Therapeutic Agents against Human Breast and Ovarian Cancer.

Researchers developed a green method to create small cadmium sulfide nanoparticles. This could have applications in medicine, bioimaging, and environmental remediation.

Bhatnagar A and Mishra A (2024).
Curr Pharm Biotechnol.
PubMed:
39034838
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