Endocrinology Studies

The Efficacy and Safety of DLBS3233, A Combined Bioactive Fraction of Cinnamomum burmanii and Lagerstroemia speciosa Plants on The Endocrine-Metabolic Profile of Women with Polycystic Ovary Syndrome: A Randomized Clinical Trial.

DLBS3233 from speciosa used for type-2-diabetes in PCOS women. Improves insulin sensitivity, metabolic and reproductive health. Consider for PCOS treatment.

Hestiantoro A et al (2024).
Int J Fertil Steril.
PubMed:
39033369

Development of ternary hybrid composites of transition metal and noble metal-based heterostructures: Ultrasensitive simultaneous electrochemical detection of bisphenol A and bisphenol S in food samples.

Ternary composites of Cu-MOF with AuAg microstructures used as a binder-free catalyst to detect BPA and BPS in food samples with high precision and recovery rate.

Nandhini C et al (2024).
Food Chem.
PubMed:
39029424

Comparable to 17α- methyl testosterone, dietary supplements of Tribulus terrestris and Mucuna pruriens promote the development of mono-sex, all-male tilapia fry, growth, survival rate and sex-related genes (Amh, Sox9, Foxl2, Dmrt1).

Researchers tested Tribulus terrestris and Mucuna pruriens supplements on young Nile tilapia. Both raised male traits and testosterone, with better growth and survival than 17α-methyl testosterone, showing potential for sex reversal in aquaculture.

Matter AF et al (2024).
BMC Vet Res.
PubMed:
39026327

Impact of khat (Catha edulis) and oral contraceptive use on telomerase levels and tumor suppressor genes p53 and p21 in normal subjects and breast cancer patients.

Study found OC use, khat chewing increase telomerase, p53, p21 in breast cancer patients. OCs increase telomerase in controls. Khat chewing is protective. Combination decreases telomerase risk in BC patients.

Atroosh F et al (2024).
Sci Rep.
PubMed:
39013992

Therapeutic Effects of Pimpinella anisum Fruit Extract on Polycystic Ovary Syndrome in a Rat Model: Emerging Role of Inflammatory Responses and Oxidative Stress.

Researchers studied the role of inflammation in PCOS development. Inflammation may contribute to symptoms, offering new treatment possibilities. Important for understanding and treating this common condition.

Dadkhah M et al (2024).
Iran J Pharm Res.
PubMed:
39005731

Supplementation with Highly Standardized Cranberry Extract Phytosome Achieved the Modulation of Urinary Tract Infection Episodes in Diabetic Postmenopausal Women Taking SGLT-2 Inhibitors: A RCT Study.

"Cranberry extract may reduce UTI recurrence in diabetic postmenopausal women taking SGLT-2 inhibitors. No impact on glycemic control or quality of life. Consider supplement for prevention."

Rondanelli M et al (2024).
Nutrients.
PubMed:
38999860

Triptonide induces apoptosis and inhibits the proliferation of ovarian cancer cells by activating the p38/p53 pathway and autophagy.

Triptonide from Tripterygium wilfordii is a potent anti-ovarian cancer agent, inducing apoptosis and autophagy through the p38/p53 pathway. It has better efficacy than platinum agents, offering a promising new treatment option.

Lou R et al (2024).
Bioorg Med Chem.
PubMed:
38964974

Characterization of the GGP gene family in potato (Solanum tuberosum L.) and Pepper (Capsicum annuum L.) and its expression analysis under hormonal and abiotic stresses.

Key enzymes GGP in potato and pepper play vital roles in plant growth and stress response. Different gene expressions and responses to phytohormones and stresses noted. Understanding these genes can help improve crop resilience.

Ding Z et al (2024).
Sci Rep.
PubMed:
38961199