Endocrinology Studies

Molecular Mechanism of Cynodon dactylon Phytosterols Targeting MAPK3 and PARP1 to Combat Epithelial Ovarian Cancer: A Multifaceted Computational Approach.

Study shows Cynodon dactylon phytochemicals target key genes in EOC pathways. Beta-Sitosterol binds strongly to MAPK3 and PARP1, offering potential for new EOC therapies.

CancerEndocrinology Cynodon dactylon
Balkrishna A et al (2024).
Cell Biochem Biophys.
DOI:
10.1007/s12013-024-01375-w
PubMed:
38961033

Effect of saponins in Panax notoginseng (Burkill) F. H. Chen on the steroid hormone levels in the chronic unpredictable mild stress model of depression in rats.

Study found that ginsenoside Rg1 and PNS from plant relieved depression symptoms in rats. Precise LC-ESI-MS/MS analysis showed positive effects on behavior and hormone levels. Potential antidepressant for humans.

EndocrinologyNeurosciencePhytochemistry Panax notoginseng
Nguyen Van K et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2371997
PubMed:
38949646

The Key Role of Plant Hormone Signaling Transduction and Flavonoid Biosynthesis Pathways in the Response of Chinese Pine (Pinus tabuliformis) to Feeding Stimulation by Pine Caterpillar (Dendrolimus tabulaeformis).

Chinese pine trees respond to caterpillar feeding by altering hormone levels, gene expression, and metabolites. Findings shed light on plant resistance mechanisms, specifically how JA activates, aiding in understanding conifer defense against insects.

EndocrinologyPhytochemistry Pinus tabuliformis
Zhao Y et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25126354
PubMed:
38928063

Using broadly targeted plant metabolomics technology combined with network pharmacology to explore the mechanism of action of the Yishen Gushu formula in the treatment of postmenopausal osteoporosis in vivo.

YSGSF boosts bone density by enhancing bone metabolism, but how it treats PMOP is unknown. Study the effects of YSGSF on PMOP to enhance treatment strategies.

ArthritisEndocrinology Panax notoginseng
Liu H et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118469
PubMed:
38914151

Exploring the role of Chinese herbal medicine in the long-term management of postoperative ovarian endometriotic cysts: a systematic review and meta-analysis.

Ovarian endometriotic cysts are a major issue for women's health, impacting quality of life and fertility. Traditional Chinese medicine, specifically herbal medicine, shows promise in treating and preventing this condition.

Endocrinology Angelica sinensis
Ding D et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1376037
PubMed:
38910886

Endogenous Hormone Levels and Transcriptomic Analysis Reveal the Mechanisms of Bulbil Initiation in Pinellia ternata.

Scientists studied the mechanisms of bulbil initiation in a medicinal plant, uncovering the role of hormones and genes. Understanding this process could improve molecular breeding techniques for this valuable species.

Endocrinology Pinellia ternata
Mou L et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25116149
PubMed:
38892337

Estrogenic Isoflavones in Clover Plants, Flower Nectar, Unripe Honeys and Mature Honeys: A Natural Biochemical Transformation of Isoflavones by Honeybees.

Scientists found estrogenic compounds in clover nectar and honey from different clover species. Red clover cultivars had highest levels. Bee enzymes may convert compounds, affecting honey quality. Research highlights potential health implications.

Endocrinology Trifolium pratense
Sultana S et al (2024).
Foods.
DOI:
10.3390/foods13111739
PubMed:
38890968
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