Researchers evaluated the potential of an ethanolic extract from the plant Roxb. to manage polycystic ovarian syndrome (PCOS) in a rat model. The extract showed beneficial effects in normalizing hormone levels and improving ovarian function. This suggests that the extract could be used as a treatment option for PCOS.
Researchers studied the pea bZIP family, a plant-specific protein involved in important biological processes. Understanding this protein can help with plant improvement and stress response strategies.
In this study, researchers investigated the effects of spinach supplementation and a hypocaloric diet on women with polycystic ovary syndrome (PCOS). They found that this intervention improved gut health, neurotrophic factor levels, and oxidative stress in PCOS patients.
Data mining, network pharmacology, and molecular docking analysis identified potential phytochemicals for ovarian cancer treatment. Apigenin, Vitamin E, Palmitic acid, Riboflavin, Isolariciresinol, and others were found to suppress tumor growth through biomarker influence. Pharmacokinetics and biosafety require further investigation.
Researchers used network pharmacology and molecular docking techniques to study the therapeutic effects of Prunella vulgaris on thyroid cancer. The findings could provide potential drug targets for treating thyroid cancer.
Scientists studied the reference genes in a medicinal plant under different hormone treatments to understand gelsenicine synthesis. They found three genes that strongly correlated with gelsenicine levels. This research will help future molecular analyses of this plant.
Celastrol, a compound from Tripterygium wilfordii Hook. f., can treat diseases. This study shows it induces ovarian insufficiency and cell apoptosis by binding to high mobility group box 1. Important for assessing celastrol's safety in female patients.
Hederagenin, a compound from Hedera helix, has anti-cancer, anti-inflammatory, anti-depressant, and anti-fibrosis properties. This study shows that hederagenin suppresses ovarian cancer cell growth, induces apoptosis, alters mitochondrial morphology, and modulates the protein Drp1 to inhibit cancer progression.