Gastroenterology Studies

Piperine induces autophagy of colon cancer cells: Dual modulation of AKT/mTOR signaling pathway and ROS production.

Piperine, from black and long pepper, shows promise as an anticancer agent for colorectal cancer. Further research needed to understand its molecular mechanisms for potential use in treatment.

Xia J et al (2024).
Biochem Biophys Res Commun.
PubMed:
38968770

Modulatory Effects of Lactobacillus paracasei-Fermented Turmeric on Metabolic Dysregulation and Gut Microbiota in High-Fat Diet-Induced Obesity in Mice.

Researchers studied the antiobesity effects of fermented and unfermented turmeric on obese mice. Fermented turmeric showed greater weight loss, improved metabolic parameters, and modulation of gut microbiota, suggesting it may be a promising antiobesity agent.

Lin WS et al (2024).
J Agric Food Chem.
PubMed:
38965062

Kidney tea [Orthosiphon aristatus (Blume) Miq.] improves diabetic nephropathy via regulating gut microbiota and ferroptosis.

Chinese herb kidney tea may offer new treatment options for diabetic nephropathy, a leading cause of end-stage renal disease. Further research needed to understand its mechanisms and potential as a therapeutic agent.

Zhou Z et al (2024).
Front Pharmacol.
PubMed:
38962302

Analysis of differential effects of host plants on the gut microbes of Rhoptroceros cyatheae.

Intestinal symbiotic bacteria in insects, including pest, play a crucial role in growth and adaptability. High-throughput sequencing revealed dominant bacteria and fungi, important for understanding adaptation mechanisms and effective pest control.

Zhang B et al (2024).
Front Microbiol.
PubMed:
38962140

Dissecting the antitumor effects of Scutellaria barbata: Initial insights into the metabolism of scutellarin and luteolin by gut microbiota.

Study investigated how gut microbiota metabolizes flavonoids in Scutellaria barbata, elucidating potential anti-tumor effects. Results inform future studies optimizing cancer treatment with SBD.

Zhang X et al (2024).
J Pharm Biomed Anal.
PubMed:
38959755