Artemisia capillaris thunb. Polysaccharide alleviates cholestatic liver injury through gut microbiota modulation and Nrf2 signaling pathway activation in mice.

Cai J et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118009

PubMed:

38447617

Network pharmacology and experimental verification study on the mechanism of Hedyotis diffusa Willd in treating colorectal cancer.

Study assessed Hedyotis diffusa Willd effects on CRC using network pharmacology & experimental validation. Identified potential targets, key genes, pathways, & validated anti-CRC effects in vitro. Important for developing new CRC treatments.

Yuan X et al (2024).

Naunyn Schmiedebergs Arch Pharmacol.

DOI:

10.1007/s00210-024-03024-8

PubMed:

38446216

Modulatory effects of fermented Polygonatum cyrtonema Hua on immune homeostasis and gut integrity in a dextran-sulfate-sodium-induced colitis model.

Li T et al (2024).

Food Funct.

DOI:

10.1039/d3fo04556k

PubMed:

38440931

Combined dilute alkali and milling process enhances the functionality and gut microbiota fermentability of insoluble corn fiber.

Jin Q et al (2024).

Food Chem.

DOI:

10.1016/j.foodchem.2024.138815

PubMed:

38428087

Morindone as a potential therapeutic compound targeting TP53 and KRAS mutations in colorectal cancer cells.

Morindone, a compound from Morinda citrifolia, shows promise as a potential anticancer agent for colorectal cancer with mutated TP53 and KRAS genes, exhibiting anti-proliferative and pro-apoptotic effects through multiple mechanisms.

Chee CW, Mohd Hashim N and Nor Rashid N (2024).

Chem Biol Interact.

DOI:

10.1016/j.cbi.2024.110928

PubMed:

38423379

Calcium Channel Inhibitory Effect of Marjoram (Origanum majorana L.): Its Medicinal Use in Diarrhea and Gut Hyperactivity.

Study evaluated methanolic extract of leaves of () traditionally used to treat diarrhea and gut spasms. Results may lead to potential new treatment options for gastrointestinal issues.

Rehman NU et al (2024).

Front Biosci (Landmark Ed).

DOI:

10.31083/j.fbl2902047

PubMed:

38420828

Enrichment of milk antioxidant activity by dietary supplementation of red clover isoflavone in cows and its improvement on mice intestinal health.

Zhang X et al (2024).

Food Chem.

DOI:

10.1016/j.foodchem.2024.138764

PubMed:

38408399

Cytotoxic and Antitumoral Effects of Methanolic Extracts of Avocado Fruit Mesocarp in Colorectal Cancer Cell Line HT29.

Researchers studied avocado extract effects on colorectal cancer cells. Avocado at different ripening stages showed antitumoral properties, with chlorogenic acid being most effective in inducing cytotoxicity, apoptosis, cell cycle arrest, and inhibiting inflammation and invasion. Results suggest potential for developing cancer treatment agents.

Gutierrez-Silerio GY et al (2024).

J Med Food.

DOI:

10.1089/jmf.2023.0112

PubMed:

38407926