Evaluation of an in vitro experimental platform of human polarized intestinal epithelial monolayers for the hazard assessment of insecticidal proteins.

The researchers tested the effects of hazardous and non-hazardous proteins on human intestinal cells grown in a lab. They also tested the effects of two insecticidal proteins on the cells and on mice. The results showed that the insecticidal proteins do not harm mammalian cells.

Zimmermann CS et al (2023).

Food Chem Toxicol.

DOI:

10.1016/j.fct.2023.114106

PubMed:

37852351

Optimizing the extraction of polyphenols from the bark of Terminalia arjuna and an in-silico investigation on its activity in colorectal cancer.

Scientists studied the plant Terminalia arjuna, which is traditionally used in India for treating diseases. Its potential pharmacological activities are being investigated for potential use in repurposing drugs. Relevant for drug development.

Adhikary T and Basak P (2023).

Curr Comput Aided Drug Des.

DOI:

10.2174/0115734099264119230925054833

PubMed:

37850546

Metagenomic characterization of the cecal microbiota community and functions in finishing pigs fed fermented Boehmeria nivea.

Fermented BN supplementation had no significant impact on antioxidants or gut structure in pigs, but did affect gene expression, bacteria abundance, and antibiotic resistance. Further research is needed.

Liang X et al (2023).

Front Vet Sci.

DOI:

10.3389/fvets.2023.1253778

PubMed:

37841475

Inonotus obliquus polysaccharide are linear molecules that alter the abundance and composition of intestinal microbiota in Sprague Dawley rats.

Study investigated how a macromolecular polysaccharide affected intestinal flora in male and female rats. Results could help determine potential gender differences in gut health and guide future research in modulating intestinal flora for health benefits.

Liu S et al (2023).

Front Nutr.

DOI:

10.3389/fnut.2023.1231485

PubMed:

37841402

Beneficial effect and mechanism of natural resourced polysaccharides on regulating bone metabolism through intestinal flora: A review.

Certain polysaccharides can improve gut microbiota and regulate bone metabolism. Factors like molecular weight and composition influence effectiveness, enhancing bone health. This can guide treatment of bone metabolic disorders.

Zhou Y et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.127428

PubMed:

37838110

Deciphering the effect of phytohormones on the phyllosphere microbiota of Eucommia ulmoides.

Phytohormones in Eucommia ulmoides leaves affect plant-microbe communication. Older leaves have lower levels of certain phytohormone components, but a more diverse microbial community. IAA and IP play key roles. The findings offer insights for sustainable agriculture and forestry management.

Shao Q et al (2023).

Microbiol Res.

DOI:

10.1016/j.micres.2023.127513

PubMed:

37837828

Cell death induction and intracellular vesicle formation in human colorectal cancer cells treated with Δ(9)-Tetrahydrocannabinol.

Hwang YN et al (2023).

Genes Genomics.

DOI:

10.1007/s13258-023-01466-7

PubMed:

37837516

Red Kale (Brassica oleracea L. ssp. acephala L. var. sabellica) Induces Apoptosis in Human Colorectal Cancer Cells In Vitro.

Red kale extract reduces cancer cell viability and proliferation, induces cell apoptosis, and may cause cell cycle arrest. Bioactive compounds in red kale contribute to its anti-cancer effect, but more research is needed to understand their specific role.

Rachwał K et al (2023).

Molecules.

DOI:

10.3390/molecules28196938

PubMed:

37836781