Gastroenterology Studies

Panax quinquefolius saponins combined with dual antiplatelet therapy enhanced platelet inhibition with alleviated gastric injury via regulating eicosanoids metabolism.

Panax quinquefolius saponin (PQS) combined with dual antiplatelet therapy (DAPT) was studied for its effects on platelet aggregation, heart attack expansion, gastric injury in rats, and its impact on arachidonic acid metabolism. PQS showed potential benefits.

Wang W et al (2023).
BMC Complement Med Ther.
PubMed:
37596586

Effects of dietary piperine supplementation on innate immunity, growth performance, feed utilization and intestinal morphology of olive flounder (Paralichthys olivaceus).

Piperine, found in black pepper, improves growth, immunity, disease resistance, and digestion in olive flounder. Optimum supplementation level is 0.5 g/kg.

Malintha GHT et al (2023).
Fish Physiol Biochem.
PubMed:
37594621

Intraspecific variation in leaf litter alters fitness metrics and the gut microbiome of consumers.

This study shows that differences in leaf litter from the same tree species can affect invertebrate consumers in ecosystems. Climate change-induced shifts in plant distributions may disrupt decomposition patterns and affect consumer fitness and behavior.

Jackrel SL and Broe TY (2023).
Oecologia.
PubMed:
37594599

Hedyotis diffusa-Sculellaria barbata (HD-SB) suppresses the progression of colorectal cancer cells via the hsa_circ_0039933/hsa-miR-204-5p/wnt11 axis.

Combination of Hedyotis diffusa and Scutellaria barbata inhibits colorectal cancer through downregulation of hsa_circ_0039933, a molecule that promotes cancer progression via the Wnt signaling pathway.

Zhu D, Yuan S and Chen C (2023).
Sci Rep.
PubMed:
37587207

Polysaccharides from Platycodon grandiflorus attenuates high-fat diet induced obesity in mice through targeting gut microbiota.

Researchers found that polysaccharides from Platycodon grandiflorus root reduced weight gain in mice, altered expression of lipid metabolism genes, and changed gut microbiota, suggesting potential as an anti-obesity treatment.

Ke W et al (2023).
Biomed Pharmacother.
PubMed:
37572640

Indicaxanthin Induces Autophagy in Intestinal Epithelial Cancer Cells by Epigenetic Mechanisms Involving DNA Methylation.

Indicaxanthin, a pigment found in prickly pear fruit, induces autophagy in colorectal cancer cells through epigenetic changes, potentially suggesting a role in gastrointestinal health.

Ragusa MA et al (2023).
Nutrients.
PubMed:
37571432