Gastroenterology Studies

Gut microbiota-based metabolites of Xiaoyao Pills (a typical Traditional Chinese medicine) ameliorate depression by inhibiting fatty acid amide hydrolase levels in brain.

XYPs are a commonly used Traditional Chinese Medicine (TCM) for treating depression. However, since they are taken orally, they may interact with gut bacteria and affect the therapeutic outcomes of TCMs. The chemical complexity of XYPs makes understanding their biological effects a challenge.

Zhang ZW et al (2023).
J Ethnopharmacol.
PubMed:
37100263

Polysaccharides from Fu brick tea ameliorate obesity by modulating gut microbiota and gut microbiota-related short chain fatty acid and amino acid metabolism.

Fu brick tea polysaccharides (FBTPSs) from fermented tea leaves reduced obesity, hyperlipidemia, inflammation, and improved gut microbiota in high-fat diet-fed rats. FBTPSs may be a promising prebiotic for obesity and dysbiosis treatment.

Zhu M et al (2023).
J Nutr Biochem.
PubMed:
37087075