Hepatotoxicity effects of Ageratina adenophora, as indicated by network toxicology combined with metabolomics and transcriptomics.
The study examined the toxic mechanisms of Ageratina adenophora (a invasive plant) using multiomics approach. The main toxic compounds were identified, and metabolites involved in amino acid and lipid metabolism were found. The plant induces liver inflammatory damage and affects nutrient metabolism and neuron conduction.
- Huang R et al (2023).
- Ecotoxicol Environ Saf.
- PubMed:
- 37948940