Genetics Studies

Overexpression of BAPT and DBTNBT genes in Taxus baccata in vitro cultures to enhance the biotechnological production of paclitaxel.

Scientists overexpressed two bottleneck enzymes (BAPT and DBTNBT) in Taxus baccata roots, resulting in higher paclitaxel production. DBTNBT line produced over four times more paclitaxel (310 mg/L) than wild type, while BAPT line almost doubled the taxane content (135 mg/L). Increased expression of key biosynthetic genes was observed.

Genetics Taxus baccata
Perez-Matas E et al (2023).
Plant Biotechnol J.
DOI:
10.1111/pbi.14182
PubMed:
37772738

Analysis of the response mechanisms of Pinellia ternata to terahertz wave stresses using transcriptome and metabolic data.

Scientists investigated the effects of terahertz radiation (THZ) on the growth of (Thunb.) Breit., a medicinal plant. They found that THZ influenced the transcriptome and metabolome of the plants, leading to changes in growth and phytohormone levels. This study enhances our understanding of plant growth mechanisms.

Genetics Pinellia ternata
Wang D et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1227507
PubMed:
37771489

Identification and Characterization of the Bicupin Gene Family and Functional Analysis of GhBCD11 in Response to Verticillium Wilt in Cotton.

The study found that the protein GhBCD11 in cotton helps degrade oxalic acid produced by the fungus V. dahliae, which causes cotton leaf wilting. GhBCD11 interacts with GhRPL12-3, a ribosomal protein. This is important for improving cotton's resistance to V. dahliae.

Genetics Gossypium hirsutum
Sun Y et al (2023).
Plant Sci.
DOI:
10.1016/j.plantsci.2023.111875
PubMed:
37769874

Lycorine inhibits pancreatic cancer cell growth and neovascularization by inducing Notch1 degradation and downregulating key vasculogenic genes.

Lycorine, a compound from Lycoris radiata herb, inhibits pancreatic cancer cell growth and reduces migration, invasion, neovascularization, and drug resistance, potentially serving as a treatment for pancreatic cancer.

CancerGenetics Lycoris radiata
Qi J et al (2023).
Biochem Pharmacol.
DOI:
10.1016/j.bcp.2023.115833
PubMed:
37769714

Exploring the extensin gene family: an updated genome-wide survey in plant and algae.

This study classified and characterized different types of extensins (hydroxyproline-rich glycoproteins) in 194 plant and algal species. It identified new crosslinking extensins and proposed an evolutionary history of these genes. This information can aid in understanding cell wall reinforcement and environmental responses in plants.

Genetics Marchantia polymorpha
Cheng SY et al (2023).
J Exp Bot.
DOI:
10.1093/jxb/erad380
PubMed:
37769205

A SUPERMAN-like Gene Controls the Locule Number of Tomato Fruit.

Researchers studied a mutant tomato plant with a gene that controls floral organ development, resulting in abnormal flowers and seedless malformed fruits. The findings contribute to understanding gene function and potential for enhancing tomato yield through genetic engineering.

Genetics Solanum pimpinellifolium
Zhang M et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183341
PubMed:
37765505

Fine Mapping and Identification of a Candidate Gene for the Glossy Green Trait in Cabbage (Brassica oleracea var. capitata).

Researchers identified a recessive gene (Bol026949) responsible for decreased cuticular wax production in a mutant cabbage. The gene plays a role in chromatin remodeling and RNA transcription, potentially affecting post-translational cellular processes and phytohormone signaling. Understanding this regulatory mechanism may benefit cruciferous crop cultivation.

Genetics Brassica oleracea
Wang P et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183340
PubMed:
37765502

First Report and Complete Genome Characterization of Cherry Virus A and Little Cherry Virus 1 from Russia.

Researchers used high-throughput sequencing to sequence and analyze cherry virus A (CVA) and little cherry virus 1 (LChV1) isolates found on interspecies hybrids in Russia. The study expands knowledge on the geographical distribution and genetic diversity of these economically important stone fruit viruses.

Genetics Prunus spp
Chirkov S et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183295
PubMed:
37765462
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