Genetics Studies

Allele mining of eukaryotic translation initiation factor genes in Prunus for the identification of new sources of resistance to sharka.

Scientists searched for genetic variations in translation initiation factors (eIF4E and eIFiso4E) in stone fruit trees to find alleles associated with resistance to the Plum pox virus (PPV). They identified new alleles in wild species that showed reduced susceptibility to PPV, potentially providing new sources of resistance.

Tricon D et al (2023).
Sci Rep.
PubMed:
37709842

Promotion of ABCG2 gene expression by neolignans from Piper longum L.

Scientists identified six compounds from Piper longum L., including licarin A and neopomatene, which showed lower toxicity and increased hABCG2 gene expression in Caco-2 cells, potentially aiding renal protection strategies.

Nishina A et al (2023).
Biosci Biotechnol Biochem.
PubMed:
37709570

Genome-wide survey, molecular evolution and expression analysis of Auxin Response Factor (ARF) gene family indicating their key role in seed number per pod in pigeonpea (C. cajan L. Millsp.).

Arpita K et al (2023).
Int J Biol Macromol.
PubMed:
37709218

Genome-wide identification of nitrate transporter 1/peptide transporter family (NPF) genes reveals that PaNPF5.5 enhances nitrate uptake in sweet cherry under high nitrate condition.

Wang J et al (2023).
Gene.
PubMed:
37708922

A haplotype-resolved chromosome-scale genome for Quercus rubra L. provides insights into the genetics of adaptive traits for red oak species.

Scientists created a reference genome of northern red oak, revealing insights into defense response genes, terpene synthesis, and plant structure. The genome offers potential for further research on bud break and stress tolerance, benefiting oak genomics and Quercus species studies.

Kapoor B et al (2023).
G3 (Bethesda).
PubMed:
37708394

Next-generation sequencing reveals altered gene expression and enriched pathways in triple-negative breast cancer cells treated with oleuropein and oleocanthal.

Oleuropein and oleocanthal from extra-virgin olive oil inhibit the growth of triple-negative breast cancer cells. They alter gene expression and affect key pathways involved in cancer progression. Further research could explore their potential as alternative treatments for this aggressive form of breast cancer.

Karousi P et al (2023).
Funct Integr Genomics.
PubMed:
37707691

Evolutionary analysis of conserved non-coding elements subsequent to whole-genome duplication in opium poppy.

Researchers studied the evolutionary patterns of regulatory and coding sequences after whole-genome duplication in opium poppy. They found that regulatory element variations drove faster changes in gene expression patterns compared to coding sequences, with tissue-specific alkaloid production evolution being influenced by changes in regulatory elements. This study sheds light on the importance of regulatory element evolution in the development of new characteristics.

Xu Y et al (2023).
Plant J.
PubMed:
37706612

Single-cell RNA sequencing profiles reveal the developmental landscape of Manihot esculenta Crantz leaves.

Researchers created a detailed map of cassava leaf cells, identifying major tissue types and key genes involved in cell differentiation. This study helps understand cassava's photosynthetic and structural characteristics, essential for improving its yield and nutritional value.

Zang Y et al (2023).
Plant Physiol.
PubMed:
37706525