Immunology Studies

Critical review on anti-inflammation effects of saponins and their molecular mechanisms.

Saponins from plants and marine life show promise for anti-inflammatory therapies via molecular actions like NF-κB regulation. They shape the gut microbiome, impacting immune regulation and metabolic health, suggesting potential dietary interventions for chronic inflammation.

Wijesekara T, Luo J and Xu B (2024).
Phytother Res.
PubMed:
38372176

An integrated in vitro approach on the enzymatic and antioxidant mechanisms of four commercially available essential oils (Copaifera officinalis, Gaultheria fragrantissima, Helichrysum italicum, and Syzygium aromaticum) traditionally used topically for their anti-inflammatory effects.

Cebollada P et al (2024).
Front Pharmacol.
PubMed:
38371914

Synergistic anti-diabetic effect of phloroglucinol and total procyanidin dimer isolated from Vitisvinifera methanolic seed extract potentiates via suppressing oxidative stress: in-vitro evaluation studies.

Researchers identified and purified phloroglucinol and total procyanidin dimer from seed extract, showing superior anti-diabetic effects in vitro by enhancing glucose uptake and suppressing oxidative stress. This natural remedy could offer a safe and economical alternative to current diabetes treatments.

Thupakula S et al (2024).
3 Biotech.
PubMed:
38371900

Artesunate-Nanoliposome-TPP, a Novel Drug Delivery System That Targets the Mitochondria, Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Stress and Inflammatory Effects.

Zhang J et al (2024).
Int J Nanomedicine.
PubMed:
38371457

Antiplatelet and Antithrombotic Activities of Lespedeza cuneata via Pharmacological Inhibition of Integrin αIIbβ3, MAPK, and PI3K/AKT Pathways and FeCl3-Induced Murine Thrombosis.

Akram AW, Saba E and Rhee MH (2024).
Evid Based Complement Alternat Med.
PubMed:
38370873