Immunology Studies

Diospyros lotus leaf extract and its main component myricitrin inhibit itch‑related IL‑6 and IL‑31 by suppressing microglial inflammation and microglial‑mediated astrocyte activation.

Researchers investigated the effects of a plant extract and its component on itch-related processes in the central nervous system. They found that the extract and component suppressed itch-related cytokines in microglia, potentially offering relief for pruritus.

Shin JY et al (2024).
Mol Med Rep.
PubMed:
39129303