Immunology Studies

Mechanistic role of Syzygium cumini (L.) Skeels in glycation induced diabetic nephropathy via RAGE-NF-κB pathway and extracellular proteins modifications: A molecular approach.

Researchers investigated the molecular mechanism of Syzygium cumini's interaction with the AGEs-RAGE-NF-κB pathway. This ancient medicinal plant may be beneficial in treating diabetic nephropathy due to its anti-glycemic, anti-glycation, anti-inflammatory, and antioxidant properties.

Apte MM, Khattar E and Tupe RS (2023).
J Ethnopharmacol.
PubMed:
38110133

The efficacy of Nigella sativa L. oil on serum biomarkers of inflammation and oxidative stress and quality of life in patients with knee osteoarthritis: A parallel triple-arm double-blind randomized controlled trial.

Amirtaheri Afshar A et al (2023).
Food Sci Nutr.
PubMed:
38107142

Investigation of antimicrobial and antioxidant activities of Chenopodium album extracts and their effects on gentamicin nephrotoxicity in rats.

This study found that extracts of aerial parts (CAE) prepared with different solvents showed antimicrobial and antioxidant activities. The ethanol extract protected against gentamicin-induced nephrotoxicity, reducing renal damage. CAE could be used as a supportive treatment for nephrotoxicity in humans.

Akbaş P et al (2023).
Food Sci Nutr.
PubMed:
38107094