Immunology Studies

Boosting impacts of Acacia nilotica against hepatic toxicity induced by gentamicin: biochemical, anti-inflammatory and immunohistochemical study.

AN extract mitigates gentamicin-induced liver damage in rats by reducing oxidative stress, inflammation, and histopathological changes. AN could potentially protect the liver from toxicity caused by gentamicin.

Althobaiti SA et al (2024).
Toxicol Res (Camb).
PubMed:
39233845

The neuroprotective role of celastrol on hippocampus in diabetic rats by inflammation restraint, insulin signaling adjustment, Aβ reduction and synaptic plasticity alternation.

Celastrol from Tripterygium wilfordii protects diabetic rats against cognitive decline by improving insulin sensitivity, glucose tolerance, and reducing inflammation in the brain. Celastrol also promotes the synthesis of synaptic proteins, enhancing cognitive function.

Zhou Q et al (2024).
Biomed Pharmacother.
PubMed:
39232386

Curculigoside Regulates Apoptosis and Oxidative Stress Against Spinal Cord Injury by Modulating the Nrf-2/NQO-1 Signaling Pathway In Vitro and In Vivo.

Curculigoside (CUR) from Curculigo orchioides reduces apoptosis and oxidative stress in spinal cord injury, promoting tissue recovery and functional improvement through Nrf2/NQO1 signaling pathway. CUR shows promise for SCI treatment development.

Hou Y et al (2024).
Mol Neurobiol.
PubMed:
39230866

Key role of Phyllanthus emblica L. fruit extract promotes ZVI/H(2)O(2) process: rich titratable acid, suitable chelating ability, and antioxidant capacity.

PFE improves ZVI/HO technology for Norfloxacin removal by enhancing efficiency and decreasing iron sludge. Key mechanism involves ROS attack, pH lowering, chelation, and antioxidant capacity. UPR concept introduced.

Lu B, Fang Z and Tsang PE (2024).
Environ Sci Pollut Res Int.
PubMed:
39230818

Chemical Compositions, Molecular Docking, Anti-Inflammatory, and Anti-Cancer Effects of the Leaf Essential Oils Isolated from Three Species of the Rutaceae Family in Vietnam.

Three Rutaceae essential oils, A. pedunculata and E. lepta are strong anti-cancer, while E. lepta is highly anti-inflammatory. Potential medicines for cancer and inflammation.

Pham TV et al (2024).
Chem Biodivers.
PubMed:
39230662

Studies on the Preparation of a Microemulsion Formulation of Matricaria Recutita Essential Oil and the Treatment of 2,4-Dinitro-Chlorobenzene- Induced Eczema in Mice by Inhibiting Inflammation.

Researchers found that Matricaria recutita essential oil shows promise in treating eczema due to its antibacterial and anti-inflammatory properties. This could lead to improved management of the disease and potential economic benefits.

Wang D et al (2024).
Curr Drug Deliv.
PubMed:
39230000