Immunology Studies

Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.

Ju A, an active component of SZS, protected against liver damage in T2DM by reducing lipid accumulation and inflammation, and enhancing fatty acid metabolism through PPARα activation. Potential treatment for NAFLD.

Zhang W et al (2024).
Chem Biol Interact.
PubMed:
39059604

Lonicera japonica Thunb. Ethanol Extract Exerts a Protective Effect on Normal Human Gastric Epithelial Cells by Modulating the Activity of Tumor-Necrosis-Factor-α-Induced Inflammatory Cyclooxygenase 2/Prostaglandin E2 and Matrix Metalloproteinase 9.

Hsieh HL et al (2024).
Curr Issues Mol Biol.
PubMed:
39057074

Ecliptasaponin A protects heart against acute ischemia-induced myocardial injury by inhibition of the HMGB1/TLR4/NF-κB pathway.

Eclipta prostrata is a Chinese herb with various health benefits, including anti-inflammatory, liver protection, and antioxidant effects. Ecliptasaponin A, found in the herb, shows strong anti-inflammatory abilities, making it beneficial for treating inflammatory conditions.

Ge S et al (2024).
J Ethnopharmacol.
PubMed:
39047883