Bacterial infections in cows cause inflammation in their reproductive systems. The compound D from Impatiens balsamina L has stronger anti-inflammatory effects than MNQ, protecting the cow's cells. The compound D acts through the steroid biosynthesis signaling pathway.
Researchers investigated the potential of Pedunculoside (PE) in treating non-small cell lung cancer (NSCLC) and its resistance to Gefitinib, a common therapy. PE, derived from Ilex rotunda Thunb., has demonstrated anti-inflammatory, lipid-lowering, and anti-tumor effects. The study aimed to understand the therapeutic effect and underlying mechanisms of PE. This research is significant as it may provide insights into new treatment options for NSCLC and combating Gefitinib resistance.
Blume, a traditional medicinal plant, has been used to treat neurological diseases due to its neuroprotective effect. To study its effect on cognition impaired by simulated weightlessness, mice subjected to hindlimb unloading were given fresh Blume orally. Behavioral tests showed significant improvement in short- and long-term spatial memory, while biochemical tests demonstrated a reduction in oxidative stress levels and maintenance of pro-inflammatory and anti-inflammatory factor balance in the hippocampus. Fresh Blume also corrected abnormal changes in synapse- and glutamate neurotransmitter-related protein. These results suggest a potential application of fresh Blume in the prevention of cognitive impairment in space.
Scientists have discovered that extracts from Physalis pruinosa and P. philadelphica plants have powerful anti-proliferative effects on cells infected with human T-cell leukemia virus I (HTLV-I), which causes adult T-cell leukemia/lymphoma (ATL). Further investigation into the compounds found in these plants led to the discovery of 13 withanolides, including six newly isolated compounds. One of these compounds, withaphysacarpin, demonstrated a comparable effectiveness to the chemotherapy drug etoposide in inhibiting the growth of ATL cells. This research suggests that withanolides could be potential candidates for the treatment of ATL.
Researchers examined the anti-inflammatory effects of bromelain, a natural enzyme from pineapple, in adults. It may be a promising alternative to reduce side effects of current anti-inflammatory drugs.