Immunology Studies

Similarities and differences between Ziqin and Kuqin in anti-inflammatory, analgesic, and antioxidant activities and their core chemical composition based on the zebrafish model and spectrum-effect relationship.

Researchers investigated the differences between two specifications of Scutellaria baicalensis, a traditional Chinese medicine. The Chinese Pharmacopoeia Commission no longer distinguishes between them, but they are still sold separately.

Sun S et al (2023).
J Ethnopharmacol.
PubMed:
36529251

Attenuation of hyperglycemia-associated dyslipidemic, oxidative, cognitive, and inflammatory crises via modulation of neuronal ChEs/NF-κB/COX-2/NOx, and hepatorenal functional deficits by the Tridax procumbens extract.

A study evaluated the effects of Tridax procumbens (cotton buttons) extract on rats with induced type 2 diabetes. The extract improved fasting blood glucose levels, insulin levels, dyslipidemia, and antioxidant status while decreasing proinflammatory mediators. The most abundant bioactive compounds identified were isorhamnetin, bixin, and lupeol. The study shows promise for TPME as an alternative therapeutic option for managing diabetic complications.

Hogan IA et al (2023).
Biomed Pharmacother.
PubMed:
36525818