Immunology Studies

Caesalpinia sappan Linn. Ameliorates Allergic Nasal Inflammation by Upregulating the Keap1/Nrf2/HO-1 Pathway in an Allergic Rhinitis Mouse Model and Nasal Epithelial Cells.

Pyun BJ et al (2022).
Antioxidants (Basel).
PubMed:
36421442

Oleracone C from Portulaca oleracea attenuates UVB-induced changes in matrix metalloproteinase and type I procollagen production via MAPK and TGF-β/Smad pathways in human keratinocytes.

Oh JH et al (2023).
Int J Cosmet Sci.
PubMed:
36415152

Salviolone protects against high glucose-induced proliferation, oxidative stress, inflammation, and fibrosis of human renal mesangial cells by upregulating membrane metalloendopeptidase expression.

Wang X, Song R and Li Z (2023).
Chem Biol Drug Des.
PubMed:
36404132

Neuroprotective potential of plant derived parenchymal stem cells extract on environmental and genetic models of Parkinson disease through attenuation of oxidative stress and neuroinflammation.

A study investigated Double Stem Cell® (DSC) for its protective effect on Parkinson's disease (PD). MPTP-induced Parkinsonism in mice and genetic model of PD in Drosophila melanogaster were used in the study. MPTP-induced motor deficits were significantly improved by DSC through dose-dependent improvements in motor, cognitive, and motor coordination. Moreover, DSC attenuated neurotoxin-induced oxidative stress and neuroinflammation in mice and Drosophila. The findings suggest that DSC could be a potential alternative treatment option for PD.

Ishola IO et al (2023).
Metab Brain Dis.
PubMed:
36401682