Immunology Studies

Anti-ischemic Effect of Monoterpene Citronellol on Experimental Stroke Models Mediated by Pro-inflammatory Cytokines.

Researchers studied the effectiveness of citronellol, a compound found in certain plants, in treating cerebral ischemia (a type of stroke). They found that citronellol has potential as an alternative therapy due to its low cost and minimal side effects. Citronellol also has various pharmacological properties that may aid in stroke treatment.

Liu X, Zhu C and Yin Y (2023).
Comb Chem High Throughput Screen.
PubMed:
36372917

Shuterin Enhances the Cytotoxicity of the Natural Killer Leukemia Cell Line KHYG-1 by Increasing the Expression Levels of Granzyme B and IFN-γ through the MAPK and Ras/Raf Signaling Pathways.

Lin JT et al (2022).
Int J Mol Sci.
PubMed:
36361609

Rhus Coriaria L. Extract: Antioxidant Effect and Modulation of Bioenergetic Capacity in Fibroblasts from Parkinson's Disease Patients and THP-1 Macrophages.

The Mediterranean plant Sumac has been found to have beneficial properties, including neuroprotection and antioxidant effects. Researchers investigated its potential neuroprotective action in Parkinson's disease (PD) by studying its effects on mitochondrial functionality. They found that Sumac extract reduced reactive oxygen species (ROS) levels, but the effect on ATP levels varied depending on the individual's genetic mutations. Sumac was also found to polarize macrophages towards an M2 phenotype, which could suggest it as a potential nutraceutical approach to PD.

Isgrò C et al (2022).
Int J Mol Sci.
PubMed:
36361562