Immunology Studies

Rosa centifolia petal extract induces endothelium-dependent and endothelium-independent vasorelaxation in rat aorta and prevents accumulation of inflammatory factors in human umbilical vein endothelial cells.

Kaneda H et al (2022).
J Food Biochem.
PubMed:
35315086

In-silico studies on wild orange (Citrus macroptera Mont.) compounds against COVID-19 pro-inflammation targets.

A study investigated phytochemicals from for their potential to inhibit inflammatory proteins that remain active in some COVID-19 survivors. Molecular docking analysis found promising inhibitory potential of the phytochemicals against COX-2, NMDAR, and VCAM-1, and MM-GBSA binding free energy estimation showed one candidate, Limonene, displayed the highest binding efficacy with VCAM-1. The study suggests that these natural compounds could be further validated in pre-clinical and clinical trials for potential use in treating post-COVID inflammation complications.

Lala M et al (2023).
J Biomol Struct Dyn.
PubMed:
35297321