Immunology Studies

Dihydromyricetin attenuates D-galactose-induced brain aging of mice via inhibiting oxidative stress and neuroinflammation.

Researchers investigated the effects of dihydromyricetin (DMY), a natural product found in Ampelopsis grossedentata, on brain aging in mice. The study found that DMY showed strong neuroprotective effects, improved spatial cognition, alleviated damage of hippocampal neurons, and inhibited senescence of hippocampal neurons. Additionally, DMY modulated oxidative stress and inflammation-related senescence of hippocampal neurons. These findings suggest that DMY may be a potential treatment for brain aging-related diseases.

Qian J et al (2021).
Neurosci Lett.
PubMed:
34022267