Immunology Studies

Ameliorative effect of Sida cordifolia in rotenone induced oxidative stress model of Parkinson's disease.

A study evaluated the effects of an extract from Sida cordifolia plant and its different fractions on rotenone-induced Parkinson's disease (PD) in rats. Biochemical and neurochemical changes were assessed in different brain regions, along with behavioral and histopathological evaluations. The most significant improvements were observed in the group treated with the aqueous fraction of the extract (AFSC). This fraction showed antioxidative properties, attenuating oxidative damage, eosinophilic lesions, and dopamine level decrease induced by rotenone. The study suggests the potential therapeutic use of AFSC in PD treatment due to its antioxidative actions.

Khurana N and Gajbhiye A (2013).
Neurotoxicology.
PubMed:
23994302