Oxymatrine attenuates sepsis-induced inflammation and organ injury via inhibition of HMGB1/RAGE/NF-κB signaling pathway.

OMT, from S. flavescens, inhibits HMGB1-mediated RAGE/NF-κB activation in sepsis, reducing inflammation and organ injury, prolonging survival rate. Important for treating sepsis.

He J et al (2024).

Drug Dev Res.

DOI:

10.1002/ddr.22219

PubMed:

38845211

Protective Effect of Aloe vera (L.) on Diabetes-Induced Oxidative Stress Linked Spermiological Co-Morbidity in Human and Rat: An In-Vitro Analysis.

Aloe vera extract protects sperm cells from diabetes-induced damage, improving motility, viability, and DNA integrity. This could enhance fertility treatments like in-vitro fertilization.

Pal D et al (2024).

Reprod Sci.

DOI:

10.1007/s43032-024-01605-9

PubMed:

38844725

Daphnoretin inhibited SCI-induced inflammation and activation of NF-κB pathway in spinal dorsal horn.

Daphnoretin, a compound from nature, shows potential in reducing inflammation and activating a key pathway after spinal cord injury. This research may lead to safer and more effective treatments for SCI.

Wu J, Lin F and Chen B (2024).

Aging (Albany NY).

DOI:

10.18632/aging.205893

PubMed:

38843384

Antioxidant, antidiabetic, and anti-inflammatory activities of flavonoid-rich fractions of Solanum anguivi Lam. fruit: In vitro and ex vivo studies.

A study on flavonoids in fruits shows potential for treating diabetes due to antioxidant and anti-inflammatory properties, as well as inhibition of key enzymes. Fraction A is most effective. More research is needed for practical application.

Ojo AB and Adanlawo IG (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e31895

PubMed:

38841505

Therapeutic effect of Periploca forrestii on collagen-induced arthritis in rats through JAK2/Nf-κB pathway.

Chinese herbal medicine has potential therapeutic effects on rheumatoid arthritis, as confirmed through chemical analysis and testing on rats. Understanding its mechanisms could lead to new treatments for this chronic autoimmune disease.

Zhang Z et al (2024).

Front Pharmacol.

DOI:

10.3389/fphar.2024.1415392

PubMed:

38841364

P-hydroxybenzaldehyde protects Caenorhabditis elegans from oxidative stress and β-amyloid toxicity.

Researchers studied the effects of -hydroxybenzaldehyde (-HBA) from on Alzheimer's disease treatment using animal models. -HBA has shown anti-inflammatory, antioxidative stress, and neuroprotective effects. This research may lead to new treatments for Alzheimer's.

Yu X et al (2024).

Front Aging Neurosci.

DOI:

10.3389/fnagi.2024.1414956

PubMed:

38841104

Phytochemicals, antioxidant ability and in vitro anthelmintic activity of crude extracts from Vitexnegundo leaves against Haemonchus contortus.

Study evaluated effectiveness of different extracts of leaves on worm eggs and larvae. Results show potential for natural anthelmintic treatment, with possibility for further research and development for parasite control.

Khan FA et al (2024).

J Parasit Dis.

DOI:

10.1007/s12639-024-01660-8

PubMed:

38840874

Correction to 'Foliar application of nettle and Japanese knotweed extracts on Vitis vinifera: impact on phenylpropanoid biosynthesis and antioxidant activity during veraison and harvest of cv. Touriga Franca'.

(2024).

J Sci Food Agric.

DOI:

10.1002/jsfa.13645

PubMed:

38840494