Immunology Studies

Portulaca oleracea L seed extracts counteract diabetic nephropathy through SDF-1/IL10/PPARγ-mediated tuning of keap1/Nrf2 and NF-κB transcription in Sprague Dawley rats.

Purslane seeds extracts have potent antioxidant properties that can protect against diabetic nephropathy. Maintaining glycemic control is essential in preventing DN.

Aziz WM et al (2024).
Diabetol Metab Syndr.
PubMed:
38811991

Breviscapine ameliorates autophagy by activating the JAK2/STAT5/BCL2 pathway in a transient cerebral ischemia rat model.

Breviscapine (Bre) from Erigeron breviscapus reduces ischemic brain damage by decreasing excessive autophagy. Activating JAK2/STAT5/BCL2 pathway improves neural recovery. Potential therapy for cerebral ischemia.

Cun Y et al (2024).
J Neuropathol Exp Neurol.
PubMed:
38804899

An Assessment of the In Vitro Antioxidant Activity of Cobalt Nanoparticles Synthesized From Millettia pinnata, Butea monosperma, and Madhuca indica Extracts: A Comparative Study.

Ryntathiang I et al (2024).
Cureus.
PubMed:
38803791

Natural Immunomodulatory Agents as a Complementary Therapy for Poxviruses.

Researchers identified polyphenolics and isoquinoline alkaloids as potential antiviral agents against monkeypox virus by targeting viral elements. Natural extracts from traditional plants also show promise. Urgent molecular studies are needed to confirm their anti-poxvirus properties.

Ali SI and Salama A (2024).
Adv Exp Med Biol.
PubMed:
38801589