Neuroscience Studies

Antidepressant-like effect of extract from Polygala paniculata: involvement of the monoaminergic systems.

This study looked at whether a plant called Polygala paniculata can potentially be used as an antidepressant. The researchers found that it has neuroprotective effects, but there is no evidence yet about its antidepressant properties.

Bettio LE et al (2011).
Pharm Biol.
PubMed:
22077163

Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations.

Researchers have found that compounds within Kadsura longipedunculata, a plant from the Schisandraceae family, enhance the GABA-induced chloride current in Xenopuslaevis oocytes expressing GABA A receptors. Thirteen compounds were identified as having GABA A receptor activity and tested in preparative scale. All but one of the 13 compounds potentiated the GABA-induced chloride current. The phytochemical profiles of petroleum ether extracts of Kadsura japonica fruits and Schisandra chinensis fruits were compared with that of K. longipedunculata. These findings suggest that compounds from K. longipedunculata have potential as therapeutic agents for conditions related to GABA A receptors.

Zaugg J et al (2011).
Phytochemistry.
PubMed:
21889177

Molecular systematics and a revised taxonomy of the onocleoid ferns (Dryopteridaceae: Onocleeae).

The study analyzed nucleotide sequences of the chloroplast-encoded rbcL gene for multiple species of ferns and their relatives. The data was analyzed using maximum parsimony and maximum likelihood criteria to determine evolutionary relationships. The results supported reclassification of two fern species and their varieties, as well as a possible reclassification of related genera. The study provides new insight into the evolutionary history and classification of these ferns and their relatives.

Gastony G and Ungerer M (1997).
Am J Bot.
PubMed:
21708636

Conservation genetics and taxonomic status of the rare Kentucky lady's slipper: Cypripedium kentuckiense (Orchidaceae).

This study analyzed 12 isozyme loci in 14 populations of Cypripedium parviflorum var. pubescens and 8 populations of Cypripedium kentuckiense to determine their genetic similarity and whether C. kentuckiense should be recognized as a distinct species. The two taxa are closely related, but C. kentuckiense has less variation and heterozygosity. It also has a unique allele and multilocus genotype, suggesting it is a distinct species, possibly originating from C. parviflorum. The isozyme data also showed restricted gene flow between the Virginia population of C. kentuckiense and others. This study supports recognizing C. kentuckiense as a distinct species.

Case MA et al (1998).
Am J Bot.
PubMed:
21680338

Species boundaries and frequency of hybridization in the Dryopteris carthusiana (Dryopteridaceae) complex: A taxonomic puzzle resolved using genome size data.

Genome duplication and hybridization shape the characteristics, behavior, and reproduction patterns of land plants like the Dryopteris carthusiana complex. This group consists of one diploid species (D. expansa) and two allotetraploid species (D. carthusiana and D. dilatata) in Central Europe. Similar appearances, adaptability, and the presence of hybrids have created ongoing debates regarding species definitions. The study explores the significance of these processes in understanding the evolution and diversity of land plants.

Ekrt L et al (2010).
Am J Bot.
PubMed:
21616872

Genome-specific SCAR markers help solve taxonomy issues: a case study with Sinapis arvensis (Brassiceae, Brassicaceae).

This study suggests that the current names and groupings of Brassiceae plants don't accurately depict their evolutionary history. Researchers believe it's necessary to revise the taxonomy and classification of these plants based on new molecular data to better understand their relationships. This conclusion comes from an analysis of several species within the Brassicaceae family. The findings provide important insight for researchers and could aid in future studies of these plants.

Pankin AA and Khavkin EE (2011).
Am J Bot.
PubMed:
21613124

Eriocaulon buergerianum extract protects PC12 cells and neurons in zebrafish against 6-hydroxydopamine-induced damage.

Researchers studied the neuroprotective effects of Ericaulon buergerianum ethanol extract (EBE), a Chinese medicinal herb known for its anti-inflammatory and antimicrobial properties. The study aimed to determine the mechanism behind EBE's abilities. The results showed that EBE had significant neuroprotective effects on cultured neuron cells under stress conditions, potentially through reducing oxidative stress and inflammation. As a result, the researchers suggest that EBE may have promising applications in treating neurodegenerative diseases.

Wang M et al (2011).
Chin Med.
PubMed:
21527031