Obesity Studies

Effect of Aruncus dioicus var. kamtschaticus Extract on Neurodegeneration Improvement: Ameliorating Role in Cognitive Disorder Caused by High-Fat Diet Induced Obesity.

The study assessed the potential of an ethyl acetate fraction from var. (EFAD) on metabolic syndrome induced by a high-fat diet (HFD). Results showed that EFAD reduces lipid accumulation, improves insulin resistance, and has ameliorating effects on obesity-induced cognitive disorder, oxidative stress, and mitochondrial dysfunction. In tests, EFAD significantly suppressed the increase of body weight and improved glucose tolerance in obese mice. The study confirmed that EFAD positively impacts the peripheral-IR and CNS-IR, which are factors in neurodegeneration such as Alzheimer's disease. The results suggest EFAD may be used for the prevention of neurodegeneration by improving metabolic syndrome caused by HFD.

Park SB et al (2019).
Nutrients.
PubMed:
31212845

Antihypertensive efficacy and safety of Vaccinium arctostaphylos berry extract in overweight/obese hypertensive patients: A randomized, double-blind and placebo-controlled clinical trial.

This study investigated the effectiveness and safety of a particular extract from V. arctostaphylos berries in treating hypertension in overweight/obese patients.

Kianbakht S and Hashem-Dabaghian F (2019).
Complement Ther Med.
PubMed:
31126570