Obesity Studies

Metabolome and transcriptome signatures shed light on the anti-obesity effect of Polygonatum sibiricum.

Researchers found that older rhizomes of a medicinal plant contain higher levels of phloretin, linoleic acid, and α-linolenic acid, contributing to an anti-obesity effect. Genetic pathways controlling metabolite accumulation were identified, providing insights for future research.

Ou X et al (2023).
Front Plant Sci.
PubMed:
37143889

Artemisia annua L. (Sweet wormwood) leaf extract attenuates high-fat diet-induced testicular dysfunctions and improves spermatogenesis in obese rats.

Artemisia annua, a medicinal plant used in Egyptian medicine, shows potential in improving testicular function, although the exact mechanism is still under investigation.

El-Sawy SA et al (2023).
J Ethnopharmacol.
PubMed:
37127141

The effects of the Rheum ribes plant extract on inflammation, extracellular matrix remodeling, and obesity suggest a therapeutic potential.

Researchers investigated the Rheum ribes L. plant to understand its molecular mechanism in treating obesity and inflammation, which are linked to the rising prevalence of Type II diabetes.

Kaya H et al (2023).
Mol Biol Rep.
PubMed:
37126207

The Prebiotic Effects of an Extract with Antioxidant Properties from Morus alba L. Contribute to Ameliorate High-Fat Diet-Induced Obesity in Mice.

L. leaf extract reduces weight gain, improves lipid accumulation and glucose sensitivity in obese mice by improving gut microbiota and reducing inflammation.

Rodríguez-Sojo MJ et al (2023).
Antioxidants (Basel).
PubMed:
37107352

Anti-obesity effect of Bioengineered Silver Nanoparticles synthesized from Persea americana on obese albino rats.

Scientists studied the effects of avocado-based silver nanoparticles on obese rats fed a high-fat diet, finding potential anti-obesity benefits.

Mohammed RA et al (2023).
Pharm Nanotechnol.
PubMed:
37106516

Phenolamide extract of apricot bee pollen alleviates glucolipid metabolic disorders and modulates the gut microbiota and metabolites in high-fat diet-induced obese mice.

Phenolamide extract (PAE) from apricot bee pollen reduced weight gain, improved glucose tolerance, and regulated gut microbiota and metabolites in obese mice. PAE could be used as a dietary supplement for obesity.

Zhang X et al (2023).
Food Funct.
PubMed:
37102591

Liver lipidomics analysis reveals the anti-obesity and lipid-lowering effects of gypnosides from heat-processed Gynostemma pentaphyllum in high-fat diet fed mice.

This study investigates how heat-processed G. pentaphyllum affects lipid metabolism in hyperlipidemic conditions, which is relevant for understanding its potential as a treatment option.

Xie P et al (2023).
Phytomedicine.
PubMed:
37094422

Corchorus olitorius extract exhibit anti-hyperglycemic and anti-inflammatory properties in rodent models of obesity and diabetes mellitus.

This review examines the effects of a plant-based remedy on obesity and type 2 diabetes. It found that the remedy can reduce blood glucose, body weight, cholesterol, and triglycerides while increasing HDL. It also decreases oxidative stress and inflammation. The remedy stimulates insulin secretion and inhibits cholesterol synthesis.

Mokgalaboni K and Phoswa WN (2023).
Front Nutr.
PubMed:
37090773