Obesity Studies

Impacts of the vegetable Urtica dioica on the intestinal T and B cell phenotype and macronutrient absorption in C57BL/6J mice with diet-induced obesity.

Including 2% U. dioica in a high-fat diet protects against fat accumulation, insulin resistance, and inflammation in mice. It also enhances immune response and reduces fat and glucose absorption.

Fan S et al (2024).
J Nutr Biochem.
PubMed:
38561081

Mulberry leaf and its effects against obesity: A systematic review of phytochemistry, molecular mechanisms and applications.

Mulberry leaf has potential as a natural remedy for obesity and hyperlipidemia, offering a safe and effective option for prevention and control of these major health issues.

Li R et al (2024).
Phytomedicine.
PubMed:
38555774

The Mechanism of the Anti-Obesity Effects of a Standardized Brassica juncea Extract in 3T3-L1 Preadipocytes and High-Fat Diet-Induced Obese C57BL/6J Mice.

Extract from berries (BJE) decreases lipid accumulation, improves heat generation and fatty acid oxidation, leading to weight loss and liver protection in mice with diet-induced obesity. Potential natural anti-obesity ingredient.

Lim JS et al (2024).
Nutrients.
PubMed:
38542756

New insight of chemical constituents in Persea americana fruit against obesity via integrated pharmacology.

Scientists used various tools to identify key compounds and targets in Persea americana fruit that could help combat obesity. The study suggests that non-fatty acids in the fruit may have significant anti-obesity effects through different pathways.

Cha MG et al (2024).
Clin Transl Sci.
PubMed:
38515346

Momordica charantia fruit reduces plasma fructosamine whereas stems and leaves increase plasma insulin in adult mildly diabetic obese Göttingen Minipigs.

Study compared blood glucose-lowering effects of Bitter gourd fruit and stems-leaves in diabetic obese pigs. Results may provide insight into physiological mechanisms and potential for human diabetes management.

Koopmans SJ et al (2024).
PLoS One.
PubMed:
38498469

Coreopsis tinctoria improves energy metabolism in obese hyperglycemic mice.

This study shows that Chinese trumpet creeper (CT) can improve energy metabolism and lower blood glucose levels in obese mice by targeting the liver. Kaempferol, a compound in CT, plays a significant role in this process.

Huangfu B et al (2024).
Heliyon.
PubMed:
38496841

The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity.

Magnolia officinalis extracts activate PPAR pathways, reduce NAFLD, promote adipose tissue browning, and combat obesity through enhanced energy expenditure and thermogenesis. Key role of FGF21 in liver-adipocyte communication.

Chu Y et al (2024).
Eur J Pharmacol.
PubMed:
38402928