Obesity Studies

Anti-Obesity Actions of Two Separated Aqueous Extracts From Arbutus (Arbutus unedo) and Hawthorn (Crataegus monogyna) Fruits Against High-Fat Diet in Rats via Potent Antioxidant Target.

In a study, two extracts from fruits of A and C plants reduced weight and adipose tissue in obese rats and improved metabolic and biochemical markers. These extracts have potential for preventing and treating obesity.

Wahabi S et al (2023).
Dose Response.
PubMed:
37275393

Coriander (Coriandrum sativum) Polyphenols and Their Nutraceutical Value against Obesity and Metabolic Syndrome.

Coriander contains bioactive compounds and polyphenols that have various health benefits. This study reviews the evidence of coriander extract as a protective agent against inflammation-related diseases like obesity, metabolic syndrome, and diabetes.

Scandar S, Zadra C and Marcotullio MC (2023).
Molecules.
PubMed:
37241925

Tuberostemonine alleviates high-fat diet-induced obesity and hepatic steatosis by increasing energy consumption.

Tuberostemonine (TS), a natural plant extract, reduces fat accumulation, improves liver function, regulates glucose metabolism, and may be developed as an anti-obesity and anti-fatty liver drug. No significant side effects observed.

Li Y et al (2023).
Chem Biol Interact.
PubMed:
37236577

Averrhoa carambola L. fruit polyphenols ameliorate hyperlipidemia, hepatic steatosis, and hyperglycemia by modulating lipid and glucose metabolism in mice with obesity.

This study investigated the effects of Averrhoa carambola L. fruit polyphenols (ACFP) on obesity-related complications in mice. ACFP showed protective effects against hyperlipidemia, hepatic steatosis, and hyperglycemia. The mechanisms of action underlying these effects were also examined.

Song H et al (2023).
J Sci Food Agric.
PubMed:
37225676

Anti-obesity potential of bioactive guided fractions of Annona squamosa linn. leaves extract: a combination of in-vitro, in-vivo and in-silico studies along with profiling of lead compounds by HPTLC MS-MS(n) method.

Bioactive fractions from [plant] show promise in reducing body weight and lipids in obese mice. Ascorbic acid and quercetin were identified in effective fractions, while stigmasterol and sitosterol exhibited strong binding to obesity-related receptors. Potential for anti-obesity treatment is suggested.

Pratap Singh R and Pattnaik AK (2023).
3 Biotech.
PubMed:
37188295

Juniper Berries Regulate Diabetes and Obesity Markers Through Modulating PPARα, PPARγ, and LXR: In Vitro and In Vivo Effects.

The methanolic extract of berries (JB) activates PPAR, PPAR, and LXR, inhibits adipogenesis, increases glucose uptake, and decreases body weight in mice. JB has potential for treating metabolic disorders and type 2 diabetes.

Chae HS et al (2023).
J Med Food.
PubMed:
37186895

Anti-obesity effects of aerobic exercise along with Rosa canina seed extract supplementation in rats: The role of irisin and adipolin.

A combination of aerobic exercise and supplementation with the hydroalcoholic extract of Rosa canina fruit seed can reduce body weight and the risks of obesity in male rats. This is achieved by up-regulating irisin and adipolin.

Taherzadeh S et al (2023).
Obes Res Clin Pract.
PubMed:
37169705

Aged black garlic (Allium sativum L.) and aged black elephant garlic (Allium ampeloprasum L.) alleviate obesity and attenuate obesity-induced muscle atrophy in diet-induced obese C57BL/6 mice.

Garlic helps with obesity and muscle atrophy. Aged black garlic and aged black elephant garlic enhance muscle growth through Akt/mTOR/p70 signaling.

Chae J et al (2023).
Biomed Pharmacother.
PubMed:
37163777